Is my first year to be a registered doctor in a hospital. I worked there in an Oncology Department. One of my patients was a 35 to 40 years old lady who suffered from Peutz-Jegher Syndrome and terminal Colon Cancer.
在医院工作，曾遇上一个患有未期肠癌的女孩子，年纪约35-40岁，她有很强的意志，她经常跟我说如果可以的话，她真的好想闯一闯！
There were 12 patients with juvenile polyps, four with hyperplastic polyps, one with juvenile polyposis and one with Peutz-Jeghers syndrome.
其中17位的主诉是长期解血便（平均3.7个月）。12位是幼年性瘜肉，4位是增生性瘜肉，1位是幼年性大肠瘜肉群症，1位是Peutz-Jeghers症候群。
Therefore, it is of great importance to study the expression regulation of VEGF to elucidate the mechanism of cancer metastasisSTK11/LKB1 (serine theronine protein kinase) is a tumor supressor gene newly identified in patients affected with Peutz-Jeghers syndrome.
因此，研究VEGF在肿瘤细胞中的表达及其调控机制对于阐明恶性肿瘤生长及远处转移特性具有重要意义。STK11/LKB1(serine theronine protein kinase11)基因为1998年从Peutz-Jeghers综合征(黑色素斑-胃肠多发性息肉综合征，PJS)患者中鉴定的抑癌基因。
Keeping this typical presentation in mind, the clinician can make an accurate pre-operative diagnosis and arrange intraoperative endoscopic polypectomy to reduce the need for repeated laparotomies.
熟悉Peutz-Jeghers Syndrome此等典型的临床及影像学上的表现，有助正确的术前诊断，提示执行术中内视镜，并尽可能切除瘜肉，以减少患者未来再接受手术的机会。
Objective: To make sure that Peutz-Jeghers Syndrome is a familial disease.
前言：目的：加强临床上对黑斑息肉病是家族性疾病的认识。
Medication Advancement of Gastrointestinal Polyposis in Patients with Peutz-Jeghers Syndrome
Peutz-Jeghers综合征胃肠道息肉的药物干预性治疗的进展
Conclusion: Mechanical obstruction and digestive tract bleeding were the main operation indication for Peutz-Jeghers syndrome.
结论机械性肠梗阻、消化道出血是外科治疗黑斑息肉综合征的主要适应症。
[Objective] To evaluate the clinical response of mucocutaneous melanosis in Peutz-Jeghers syndrome to Q-switched Alexandrite laser therapy.
[目的]探讨调Q紫翠玉激光治疗Peutz-Jeghers综合征口唇色素斑的临床疗效。
[Conclusion] Q-switched Alexandrite laser therapy is both safe and effective for mucocutaneous melanosis in Peutz-Jeghers syndrome.
[结论]调Q紫翠玉治疗口唇色素斑，安全而有效。
Endoscopy should be performed regularly and the high-frequency electroresection is an effective therapy in disposing intestinal polyp. Screening can also improve the efficacy of Peutz-Jeghers syndrome.
定期复查内镜，以内镜高频电凝积极处理肠息肉，以及筛查肿瘤是提高Peutz-Jeghers综合征远期疗效的有效方法。
Objective To analyze the clinical features, imaging manifestation, pathological findings, endoscopic findings and treatment regimen of Peutz-Jeghers syndrome (PJS).
目的探讨黑斑息肉病的临床、影像、病理和内镜表现和治疗对策。
Objective To study the significance of β catenin, p53 and PCNA in Peutz Jeghers syndrome (PJS) harmatoma.
目的研究黑斑息肉综合征（PJS）错构瘤中βcatenin、p53、PCNA表达及在发病和癌变中的意义。
Objective To facilitate a better understanding of the progress in the research, diagnosis and treatment of Peutz Jeghers syndrome (PJS).
目的介绍黑斑息肉综合征（PJS）的研究和临床诊治进展。
Methods The treatment and diagnosis were retrospectively analysed in 28 cases of Peutz - Jeghers syndrome.
方法回顾性分析28例黑斑息肉病的诊断及治疗。
The Study of the Diagnoses and Therapy for 6 Cases of Peutz-Jeghers Syndrome Objectives To investigate the diagnostic methods and reasonable treatment of Peutz - Jeghers syndrome (PJS).
黑斑息肉综合征6例的诊治分析目的探讨黑斑息肉综合征（Peutz-Jegherssyndrome，PJS）的诊断方法和合理的治疗方案。
Reporting 7 cases of PeutZ & Jeghers syndrome (PJS).
报告黑斑息肉综合征（PJS）患者7例。
Regular endoscopy and PSD is an effective therapy in improving the long - term outcome of Peutz - Jeghers syndrome.
应定期复查内镜，行PSD是提高黑斑息肉病远期疗效的有效方法。
[Method] 2 cases of Peutz-Jeghers syndrome underwent Q-switched Alexandrite laser therapy and the clinical response was evaluated.
[方法]以调Q紫翠玉激光治疗2例患者，剂量6-8J／cm2。
Bioinformatics Analysis of the Transcriptional Regulation of Peutz-Jeghers Syndrome Gene STK11/LKB1
PJ综合征疾病基因STK11/LKB1转录调控的生物信息学分析
Peutz-Jeghers syndrome (PJS) is an autosomal dominant disorder characterized by multiple hamartomatous polyps of gastrointestinal tract, muco-cutaneous pigmentation and increased risk of malignancies in different organs.
Peutz-Jeghers综合征（PJS）又称黑斑息肉综合征，是一种以皮肤粘膜黑斑、胃肠道多发息肉及恶性肿瘤发生率增加为特征的常染色体显性遗传病。