Methods and Results— Here, we report that induction of a metabolic stress response with adenosine monophosphate kinase prevents oxidative endothelial cell injury.
方法和结果—本次研究我们提出，代谢应激反应的诱导和腺苷激酶可以防止氧化内皮细胞的损伤。
The role of erythropoietin on angiogenesis and retinopathy is beginning to be defined, and it has been shown to promote both endothelial cell proliferation and vessel growth. Erythropoietin also has cytoprotective capabilities and is able to protect vascular cells and neurons from apoptosis. The authors point out that, in the eyes, erythropoietin levels are increased in the vitreous of patients with proliferative diabetic retinopathy, and mouse studies have shown that inhibiting erythropoietin in the proliferative phase can inhibit retinal neovascularization.
红血球生成素在血管新生作用与视网膜病变的角色目前正在研究中，目前显示它可以促进内皮细胞增殖与血管生长；红血球生成素也具有细胞保护的作用，且其能够保护血管细胞与神经细胞免於细胞凋亡；作者指出，在眼睛，罹患糖尿病视网膜增殖性病变病患，其水晶体内的红血球生成素浓度是增加的，老鼠的动物模式研究已经显示，抑制增殖期的红血球生成素可以抑制视网膜血管新生。
Our results demonstrate that chemokines present in the uterus can support pbNK cell migration through human endothelial and stromal decidual cells.
我们的研究结果表明子宫中的化学因子支持pbNK细胞通过人的内皮和间质蜕膜细胞迁移。
In summary, we found a P-I SVMP with a smaller molecular weight, named trimpase, and it can inhibit endothelial cell adhesion and cleave adherens junction to induce endothelial cell apoptosis.
而trimpase 会藉由裂解ECMs而抑制血小板凝集。
AIM: To observe the changes of corneal endothelial cell if affected by trabeculectomy.
大 目的：观察小梁切除术对角膜内皮细胞有无影响。
Objective To explore a new endothelial cell separation method.
目的 探索一种新的内皮细胞分离方法。
The whole course of treatment group was 8 weeks. By means of comparative the curative effect for patients before and after therapy between treatment group and control group which treated with Bu-yang-huan-wu decoction, the observations on effects were made. The indexes of curative effects included: clinical symptoms integrals; nervus dysfunctions system, cognitive function, viability, quality of life index, blood glucose, Glycosylated Hemoglobin A-1c(HbA1c), insulin sensitivity index, blood-lipid, blood rheologp (whool blood riscosity, plasmic riscosity, fibrinogen), the functions of endothelial cell, serum inflammatory index (c-reactive protein, CRP), etc.
临床研究方法：以30例2型糖尿病并脑梗塞患者为研究对象，口服益消复瘫汤8周，按积分记录症状体征，检测疗效指标：包括中医证候疗效，神经功能缺损水平，认知功能障碍水平，日常生活活动能力，生存质量评估，血糖，糖化血红蛋白(HbA1c)，胰岛素敏感指数，血脂指标(TC、TG、HDL、LDL)，血液流变指标(全血比粘度、血浆比粘度、纤维蛋白原)，内皮功能，血清炎性指标等。
Vascularendothelial cells are the target cells of angiogenesis that has direct relationwith tumor angiogenesis. While tumor angiogenesis is regulated by the rigorous andcomplicated signal network in the microenvironment, numerous previous researchfocused on tumor cells. Until recently, CAFs have been verified playing animportant role in recruitment, proliferation of VEC and vascular bud shaping in thestudies of breast and prostate carcinoma. However, no reports about the effects ofCAFs on angiogenesis of OSCC has been published.
血管内皮细胞(vascular endothelial cell，VEC)是血管生成的靶细胞，肿瘤血管新生受微环境中庞大精密而复杂的信号网络调控，过去的研究多集中于肿瘤细胞对其的调控作用；新近研究发现，CAFs在肿瘤VEC的募集、增殖和血管芽的形成中发挥重要作用。
Vascular endothelial cells and smooth muscle cells are important cell sources for vascular tissue engineering.
所培养的血管内皮细胞和平滑肌细胞为研究组织工程血管提供了细胞来源。
No serious, vision-threatening, irreversible complication such as keratectasia or progressive endothelial cell loss was observed.
未发现严重的危害视力的不可逆性并发症，如角膜扩张或进行性内皮细胞丢失。
The mechanism probably is that Pishang can inhibit the growth, movement and adheresion to extracellular matrix and endothelial cell of liver tumor cells, up-regulate the expression of nm23, down-regulate the expression of CD44, MMP-2, and inhibit the tumor neovascular by supressing the vascular endothelial cell, down-regulating the expression of VEGF, damaging the primitive mesenchymal cells and inhibiting neovascular gemmation.
砒霜具有明显的抗肝癌细胞作用，并有一定的抗侵袭与转移作用，其机制可能与其能抑制肝癌细胞增殖、迁移、阻止肝癌细胞与细胞外基质和内皮细胞粘附、上调肿瘤转移抑制基因nm23表达、下调肿瘤侵袭分子CD44、MMP-2表达以及通过抑制内皮细胞增殖、下调VEGF表达、损伤间充质细胞、阻止新生血管芽生等途径从而抑制肿瘤新生血管形成有关。
Human placenta mesenchym of full-term deliveries containes CD34(superscript +) and CD133(superscript +) cells. There is no endothelial progenitor cell in the villous capillary of the mature placenta.
人足月胎盘组织间质中存在CD34和CD133细胞，晚期胎盘绒毛血管无内皮祖细胞存在。
In oder to verify that CPE in endothelial cells was caused by shimen virulent strain ofCSFV, in this experiment RT-PCR and nPCR assay was used to identify viral E2 gene in theendothelial cell inoculated shimen virulent strain of CSFV.
为了确证血管内皮细胞 CPE 是否由 CSFV 石门株引起，将 CSFV 石门株接种于培养的猪血管内皮细胞，从接种后 24h，48h 和 72h 的血管内皮细胞和阴性对照血管内皮细胞提取细胞 RNA，经 RT-PCR 和 nPCR 扩增 CSFV 的 E2 基因。
Endothelial cell expression of vaso-constrictors and growth factors is regulated by smooth muscle cell-derived carbon monoxide ［J］.
体外合成的反义寡核苷酸可特异与某些基因的DNA或mRNA结合，以阻止该基因的转录或翻译，达到削弱该基因的目的。
The present study analysis whether CRP could directly induce inflammation in endothelial cells, analysis what kind of effects CRP provide on cellular signal transduction in endothelial cell by gene array, and isolate LDL by one step of density gradient centrifugation, generate E-LDL by degrading LDL with multiple enzymes, direct fluorescent labeling CRP and LDL, investigate whether CRP play as intermediator in atherosclerosis.
本课题目的在于探讨CRP在脂质参与的动脉粥样硬化形成中是否起到介质作用，主要通过检测直接CRP能否诱导内皮细胞炎症表现，基因芯片分析CRP对内皮系统的细胞信号转导通路的影响，探讨CRP参与调控内皮系统炎症过程的主要机制，并且通过一步法密度梯度离心分离LDL，复合酶处理生成E-LDL，直接荧光标记CRP和LDL，分析CRP介导脂质紊乱尤其是LDL代谢产物参与动脉粥样硬化早期形成的作用。
Fewer neovascularities, inflammatory cells and smaller caliber in artesunate treatment groups were observed under the microscope. 3. The endochylema of the neovascularization`s endothelial cell is abundant and nucleus of the neovascularization`s endothelial cell is big in the control group under transmission electron microscope. The neovascularization`s endothelial cell appearance immature and apomorphosis in the artesunate treatment group.
治疗组角膜混浊程度较对照组明显减轻。2生理盐水对照组角膜病理组织切片可见新生血管丰富，管径大，管腔充盈，炎症反应较大，治疗组新生血管少，管径小，炎症反应轻。3电镜下对照组新生血管内皮细胞胞浆丰富，核大。
Objective To study the expression and significance of dendritic cells and vascular endothelial growth factor in human bladder cancer.
目的 探讨人类膀胱癌组织中树突状细胞(dendritic cell，DC)、血管内皮生长因子的表达及其意义。
Hepatocellular carcinoma; dendritic cell; vascular endothelial growth factor; immunohistochemistry
肝细胞肝癌；树突状细胞；血管内皮生长因子；免疫组织化学
The biologic activities of Ang-1 protein were tested with the chick chorioallantoic membrane vasiformation experiment and the conditional culture of vascular endothelial cell. The result showed that the pure rMSCs were obtained with the combination of density gradient centrifugation and adherent culture, the Ang-1 gene was integrated into rMSCs genome, and transcribed and expressed correctly.
结果显示我们通过密度梯度离心和贴壁培养相结合的方法获得了比较纯的rMSCs，慢病毒感染后Ang-1可整合至rMSCs基因组中，并可正确转录和表达，所表达的Ang-1蛋白具有促进血管生长的生物学活性。
GXBD might balance the production of NO and ET by vascular endothelial cell, and prevent elevation of segment ST and myocardiac damage. This is one of mechanism to protect myocardial ischemia.
栝蒌薤白半夏汤能调节心肌缺血大鼠ET和NO分泌的失衡，防止心肌损伤，可能是其保护心肌缺血作用机制之一。