G/ml. After wt-p53 transfection and VCR treatment, the number of Bel-7402 cells was decreased; the cells were swollen severely with irregular projections; pyknosis, karyorrhexis and karyolysis were observed. After wt-p53 transfection, the expression of mdr1 and P-gp in Bel-7402 cells was down-regulated remarkably, and the expression of TopoⅡα was up-regulated.
形态学检查转染细胞，在VCR作用下细胞数明显减少，细胞散在不成片、细胞高度水肿、胞体不规则突起，可见核固缩、核裂解、核溶解。p53基因对Bel-7402细胞的mdr1/P-gp的表达有明显的抑制作用，对TopⅡα基因的表达有上调作用，对GSTπ、MRP基因表达没有影响。
He CR rate is much higher in TOPOⅡα positive group than those in negative group; ⑹ The drug sensitivity test is correlated with outcome of chemotherapy with an overall predictive rate of 86.67%, 75%, a positive predictive rate of 92.31%, 83.33%, a negative predictive rate of 50%, 50% in AML and CML; ⑺ CSA significantly potentate the cytotoxicity of DNR, MXT, VCR and VP-16 to K562/A02 resistance cell line which overexpress PGP, and MXT to the leukemic cells of patient whose leukemic cell overexpress PGP; ⑻ BSO did not increase the depressive rate of anthracycline and alkaliod to PGP overexpressed K562/A02 cell line and the leukemic cells which overexpress PGP, MRP1 and GSH, But significantly improve the depressive rate of AS2O3 and AS4S to leukemic cells.
OPOⅡα阳性白血病组的CR率为93.75%，明显高于阴性组的58.33%；⑹ CSA可以明显增加柔红霉素、米托蒽醌、长春新碱和足叶乙甙对PGP表达阳性K562/A02耐药细胞及患者白血病细胞的细胞毒性作用，但不影响对MRP1、GSH高表达患者白血病细胞的毒性作用；⑺ BSO不增加蒽环类、长春碱类、表鬼臼类等天然药物对表达不同耐药蛋白白血病细胞的抑制率，但明显增加了AS2O3和AS4S4对白血病细胞的抑制率。
Golden Melody Awards in cooperation with Jolin-off, through Daniel Poeter first at the scene VCR sent best wishes, Fiona Sit and Khalil Fong days after the request has not only taught himself to sing, also scheduled for the early to Taiwanto be invited to dine when Jolin.
在金曲奖上与Jolin合作过的Daniel Poeter第一个通过现场VCR送上祝福，薛凯琪和方大同不但要求天后教自己唱歌，还早早预定了去台湾时Jolin要请吃饭。
The BT325/VCR cell lin e showed a overexpression of P-glycoprotein and P-glycoprotein medicated typic al multidrug resistance phenotype.
BT325／VCR细胞无药培养4周后，对VCR的耐药性未见明显降低，其IC50为206.99。
The results showed that in certainconcentration, the CAs and CaMAs, which are used alone or combined withDoxorubcine, could inhibit the proliferation of K562/VCR cells(P＜0.01)andsignificantly increase the inhibition effect with their level rising up showingthere exists close dependence on the concentration.
结果表明：在一定的浓度时，CAs及CaMAs单独或与阿霉素合用均可抑制K562/VCR细胞的增殖（P＜0.01），并且随着浓度的增加抑制作用增强，呈明显地浓度依赖关系。
And don't worry, the intuitive VCR style user interface is very easy to use.
不必担心，直观的VCR风格的用户界面是非常容易使用。
Ease of possession is connected with price, which includes the initial cost and two other issues as well: 1 financing terms, interest rates, lines of credit and/or acceptance of credit cards, and 2 warranties-will the customer's VCR break down six months from now or can he or she expect it to operate trouble-free for several years?
便于占有量与价格，其中包括最初的费用以及其他两个问题：1融资条件，利率，信贷额度和/或接受信用卡和2保证将客户的录象机破裂，从现在起的六个月或他或她期望它能经营摆脱烦恼几年？
The retreat slicing blast of VCR was replaced by side blasting with more than 10 thousand tons of blasted ore each time. And the blast patten in VCR has been improved.
用侧向崩矿取代VCR法退后分层落矿方式，每次爆破矿石量可达数万吨至10万吨，改进了VCR法的爆破崩矿方式。
That was the case with VCRs, video cassette recorders.
这也是VCR所面临的事情。
VCR element was introduced in melting transport zone of intermeshing counter-rotating twin screw extruder in the second part of this paper.
结果表明：在机筒上引入销钉后的元件比常规螺纹元件有更好的分布和分散混合能力。
VTR for automotive interior seat heating, dimmers, wipers and various control rotary operation feeling good air-conditioning, electronic toys, microwave ovens, rice cooker, car navigation devices, LCD monitors, remote control machines and other portable electronic audio volume, sound quality control of GM in a variety of electronic audio equipment, office equipment, communications equipment, measuring instruments, TV, VCR and other operating.
VTR 用于汽车室内的座席加热，调光器，刮水器等各种控制良好的旋转操作感觉空调、电子玩具、微波炉、电饭锅、汽车导航器、液晶监视器、遥控器等各种电子机器便携式音响的音量、音质控制用通用于电子化的各种音响设备、办公设备、通讯设备、测量仪器、TV、录像机等各种操作。
Chemotherapy sensitivity on adriamycin, cisplatinum, fluorouracil, mitomycin C, dacarbazine, vincristine, met...
结果患者瘤组织对ADM、DDP、5-Fu、MMC、DTIC、VCR和MTX的不敏感率分别为41.18%、17.65%、47.06%、50.00%、76.47%、61.76%和52.94%。
Planted membrane into the mice which was inoculated EAC, observed the effects of membrane on tumor and SOD of serum; the results suggested that CCNU, VCR membrane significantly inhibited the growth of EAC tumor and enhanced the activity of SOD of serum compared with control group. Put release solution of membrane into K562 cells to incubate together, then observe the effects on apoptosis by TEM (Transmision Electric Microscope) and agrose gel electrophoresis analysis of cleavage DNA; the results showed that CCNU, VCR membrane groups had more apoptosis cells compared with control group. Put release solution of membrane into K562 cells to incubate together, then observed the effects on inhibitory ratio of K562 cells by MTT method; the results suggested that CCNU, VCR membrane sinificantly enhanced the inhibitory ratio of K562 cells compared with control group.
将控释膜埋植入荷瘤小鼠体内，观察对鼠艾氏实体瘤的抑制作用以及对血清SOD的影响，结果与阴性对照组比较，CCNU、VCR药膜均明显抑制肿瘤的生长、升高了小鼠血清SOD活性，SOD活性升高提示药膜对肿瘤生长有抑制作用；通过电子显微镜和DNA提取及琼脂糖凝胶电泳法观察药膜对K562细胞凋亡的影响，结果表明电镜观察CCNU、VCR药膜组发生细胞凋亡的细胞数明显高于阴性、阳性对照组，VCR持续作用120h后，可以使K562细胞出现DNA梯形条带，但不是十分明显，提示有部分细胞凋亡发生；药膜于体外细胞培养液中进行释放，释放液与K562细胞共同培养，MTT法观察对K562细胞的抑制率，与阴性对照组比较，CCNU、VCR药膜的三个剂量组均对K562细胞有较强的抑制作用。
Objective:To study the cytotoxic activity of DNR and VCR on HL-60 cell line in vitro.
目的 ：观察柔红霉素、长春新碱联合应用在体外对人急性髓系白血病细胞株(HL—60)的相互作用。
Before the video played, Lindelof and Cuse recounted a story in which the film was sent to them after being found in a building in Narvik, Norway that was set to be demolished (possibly the Hanso Foundation headquarters).
在COMIC CON上播出这段VCR时，主创人员说这个片子是有人在挪威Narvik的一个已被拆除的建筑里发现并寄给他们的，被发现时已经只剩片段。
This setting control how loud a tape will sound when play back on the vcr during a conference.
该设置可以控制在一次视像会议进行当中回放vcr时的音量。
Results twenty-six clones of hybridoma whose supernatant had the ability to bind sgc7901/ vcr were obtained from 3268 clones after 21 times cell fusing. and one mab of interest, which was named mgr1, was selected by immunohistochemistry and mdr reversal test of mab. mgr1 stain was stronger on sgc7901/ vcr than on sgc7901, and could enhance the cytotoxity of 5-fu and adr on sgc7901/ vcr.
结果 经过21次融合获得了26株培养上清能与sgc7901/ vcr结合的杂交瘤克隆，经免疫组化和单克隆抗体逆转耐药实验发现其中一株mab在sgc7901/ vcr膜表面及胞内的表达显著高于其相应的药物敏感细胞sgc7901，并能部分逆转sgc7901/ vcr对adr和5-fu的耐药性。
Either Wall Street or Secret of My Success are on their way to your VCR.
我是一粒漂浮不定的尘埃，我找不到我的阳光地带！
The 3D Newtonian isothermal flow of normal double-thread screw element, normal triple screw element and VCR element was simulated.
第二部分则是在熔体输送段引入VCR元件，通过对常规双头螺纹元件、三头元件和VCR元件流道进行三维等温流场的模拟与分析。
The numerical analyses also showed that VCR element has the best distribute mixing effect and normal double-thread screw element take the second place, normal double-thread screw element is the weakest among them.
模拟结果表明：常规双头螺纹元件分散混合能力最强，常规三头螺纹元件次之，VCR元件最弱；而VCR元件分布混合能力最强，常规三头螺纹元件次之，常规双头螺纹元件最弱。