And the amino acid sequence contains highly conserved GTP-binding domains and a fully conserved effector domain of human RRas member.
同时拥有人类RRas基因高度保守的结合GTP的结构域和完全一致的效应结构域。
Results After screening, 59 subtracted library clones were isolated which were specific for strain VIB72, and the DNA sequences of these clones were determined. Seventeen fragments showed high homology to the genes of known functions in other bacteria. This includes soluble lytic murein transglycosylase, mobilization protein, transposase (IS66), resistance-related protein (metallo-beta-lactamase and acetyltransferase family), toxin protein (DT-201 and alveicin A immunity protein), ATP-dependent endonuclease of OLD family like protein, SocE and GTP-binding protein HflX (high frequency of lysogenization).
通过对差减文库筛选，分离到59个对菌株VIB72的克隆，并对这些克隆的DNA序列进行了测定。17个基因片断与其它细菌的已知功能的基因有较高的同源性，其中包括可溶性溶胞壁质转糖基酶、转移蛋白MobA和MobC、转座子IS66、抑制相关蛋白（金属β-内酰胺酶和乙酰转移酶家族）、毒素蛋白（DT-201和alveicin A免疫蛋白）、与OLD 家族相似的ATP依赖性核酸内切酶以及SocE 和GTP结合蛋白HflX。
Next, BALB/c mice were orally infected with Y. pseudotuberculosis and its ompR mutant to study metabonomic variation of different intestine-associated organs after 24 h infection. The results showed that a majority of metabolites were decreased during this acid adaptation process, but phosphoenolpyruvate, 5'-GMP, 5'-AMP, 5'-UMP, GDP/GTP of wild type strain and lactate, Tyr, phosphoenolpyruvate, 5'-AMP、GDP/GTP of the ompR mutant strain were increased.
为了探讨病原细菌感染动物后特别是在酸性环境下代谢物的变化规律，首先在体外模拟假结核耶尔森氏菌及其全局性调控因子OmpR突变株在适应酸性环境时所引起的菌体自身的代谢变化，然后通过BALB/c小鼠口服感染耶尔森氏菌，研究小鼠感染病原细菌24h后各种相关器官的代谢变化。
Mice of group 5 and 6 were given distilled water and GTP solution (4mg/mouse) respectively orice a day for five days...
因而测定二甲基肼诱发小鼠大肠隐窝上皮细胞微核和凋谢，可作为抗结肠致癌物的快速筛选方法。
The homophilic interaction between molecules of osRACD protein appeared to be mediated by Mg〓 and molar concentration of osRACD protein.
并且，通过实验证明，osRACD蛋白分子间的聚合，有可能刺激了其自身的GTP酶活性。
In addition, GTP treatment inhibited the auto-oxidation of 6-OHDA and scavenged oxygen free radicals in a dose- and time-dependent manner.
溶液实验证明，茶多酚对6-OHDA的自氧化有浓度-时间依赖性抑制作用。
The activity of the G protein depends on whether it is bound to GTP or bound to GDP.
Figure 35.18 单体G蛋白结合GTP激活，结合GDP失活它们的活性被其他蛋白所控制，激活为红，失活为蓝。
In Saccharomyces cerevisia, YPT1 GTPase regulates the transportation of proteins from ER to Golgi.
在酿酒酵母中，GTP结合蛋白YPT1调节蛋白质从内质网到高尔基体的运输。
ADP ribosylation factors are critical in the vesicular trafficking pathway. ARF activity is controlled by GTPase-activating proteins.
ADP核糖基化因子在膜泡运输中具有重要作用，其活性受GTP酶活化蛋白的调控。
Keywords: vesicular transport; ADP ribosylation factor; GTPase-activating protein; secreted alkaline phosphatase
中文关键词：膜泡运输；ADP核糖基化因子；GTP酶活化蛋白；分泌的碱性磷酸酶
Objective To investigate in Chinese population the relationship between GTP cyclohydrolase 1 gene mutation and phenotypes of dopa-responsive dystonia.
目的 分析国人多巴敏感性肌张力障碍患者三磷酸鸟苷环羟化酶1（GCH-1）基因突变与表现型的关系。
We found that AGE time- and dose-dependently decreased nitric oxide production and GTP cyclohydrolase I/inducible NO synthase activation.
从实验结果中我们发现高度糖化终产物随著时间及浓度增加的刺激下会明显抑制NO生成及GTP cyclohydrolase I的表现量，并且减少诱导型一氧化氮合成酶的活性。
According to our previous study, we found that coactivator RNF4 is involved in the GTP cyclohydrolase I gene expression and we defined the RNF4-responsive element on GCH proximal promoter as a CCAAT-box.
根据我们过去的研究，我们发现RNF4参与GCH此基因的转录表现，而且这样的活化过程是藉由GCH基因上游启动子中的CCAAT-box来达成。
GTP cyclohydrolase I is the rate-limiting enzyme for de novo BH4 synthesis.
GTP GTP环水解酶Ⅰ是BH4合成的限速酶。
The first step of the plant pterin branch is catalyzed by GTP cyclohydrolase Ⅰ and the first step in the conversion of chorismate to pABA is mediated in plants by aminodeoxychorismate synthase.
叶酸分子是由喋呤和对氨基苯甲酸从头合成的，二者合成的关键酶腺苷三磷酸环化水解酶和氨基脱氧分支酸合成酶已得到克隆鉴定。
Vav1 acts as the guanine nucleotide exchange factorfor Rho-family GTPases and can mediate several cytoskeletal-associated cellular processes.
Vav1主要作为Rho家族GTP酶的鸟苷酸交换因子，因而可以参与多种和细胞骨架相关的信号通路。
RhoA is an important member of Rho GTPases and is involved in leukocyte migration.
RhoA是Rho GTP酶的重要成员，其参与白细胞移动。
The cytoplasmic proteins with ATPase or GTPase activities such as motor protein, G—protein and molecular chapero...
细胞质中具有ATP酶或GTP酶活性的蛋白，是当前生化学家和细胞生物学家研究的热点和要点之一。
These papers provide the details of the mechanisms of GTP-dependent elongation and translocation that will be discussed in class.
这些文章提供了课堂上讨论到的GTP依赖型延伸与移位过程的细节。
The binding reaction brings SOS to the membrane, and thus into the vicinity of Ras. SOScauses the GDP on Ras to be replaced by GTP, which is sufficient to activate Ras. Grb2 is not the only
SHC结构域（尤其是C-Src的SHC结构域）的另一个作用是与细胞骨架蛋白反应，从而引起细胞结构的改变。