Topotecan is an effective agent for SCLC when used as monotherapy or in combined treatment, but myelosuppression such as leucopenia and thrombopenia was relatively severe. Although it has been recommended as a second-line agent for recurrence of sensitive SCLC, more clinical trials are needed to define its role in first-line treatment.
拓扑替康治疗小细胞肺癌有确切临床疗效，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，但具有相对高的致白细胞和血小板下降的骨髓毒性，已被认为是治疗化疗敏感的小细胞肺癌患者复发的二线推荐药物，但是作为一线用药仍然需要更多的实践来证实。
Subsequently, the characteristics of the included articles were appraised and extracted.
纳入以肺组织病理诊断为金标准，对比NSE 诊断 SCLC 的诊断性试验。
Only half of people who have SCLC survive for four months without chemotherapy.
只有一半的人，小细胞肺癌生存时间为四个月，如果没有化疗。
Most of those who survive have limited stage SCLC.
大多数人有限的生存阶段小细胞肺癌。
The peripheral blood samples were collected from 22 patients of SCLC and 10 healthy individuals.
结果表明，在22例小细胞肺癌病人的外周血中有18例(81.8％)检测到了NMB-R基因的表达，但在10个正常人的外周血中检测到2例为阳性。
Of all patients with SCLC, only 5-10% are alive 5 years after diagnosis.
所有细胞肺癌患者中，只有5-10%活着诊断后五年。
Till 1959, SCLC just is considered as a kind of independent disease.
直到1959年，SCLC才被认为是一种独立的疾病。
The dianostic possibility of ctand CT combined with puncture biopsy of SCLC were 80% and 90% respectively.
CT螺旋扫描结合CT导向经皮穿刺活检与纤维支气管镜肺活检是SCLC确诊的主要手段。
The dianostic possibility of ctand CT combined with puncture biopsy of SCLC were 80％ and 90％ respectively.
结果：肺内肿块、肺门与纵隔淋巴结广泛肿大，是SCLC的CT表现特点，CT诊断的可靠性大约为80％，结合经皮穿刺活检可提高到90％。
The dianostic possibility of ctand CT combined with puncture biopsy of SCLC were 80％ and 90％ respectively. Conclusion CT scan combined with puncture biopsy is the main approach to diagnose SCLC.
CT螺旋扫描结合CT导向经皮穿刺活检与纤维支气管镜肺活检是SCLC确诊的主要手段。
There are close correlations between the expression of the c-Kit protein and the development of SCLC and the prognosis of patients.
c-Kit蛋白的表达与SCLC的发生、发展及肿瘤大小及预后密切相关。
Adenocarcinoma is mainly primary MDR while SCLC and squamous cell carcinoma are mainly secondary to chemotherapy.
肺鳞癌和小细胞肺癌可能为获得性MDR1耐药，肺腺癌是原发性MDR1耐药。
No deletion was observed in 37 cases of SCLC and 14 paracancerous lung tissues.
小细胞肺癌和癌旁正常肺组织中无p16 E2的缺失。
The sensitivity and specificity of PTN in patients with SCLC were 90.9% and 94.1% respectively.
PTN是一种有效检测肺癌的标志物，尤其在SCLC的血清中升高更明显，因此血清PTN可作为早期诊断SCLC的指标。
A common paraneoplastic syndrome associated with SCLC is the production of a hormone called adrenocorticotrophic hormone by the cancer cells, leading to oversecretion of the hormone cortisol by the adrenal glands (Cushing`s Syndrome).
一个共同的小细胞肺癌是癌症与制作一个称为促肾上腺皮质激素激素的癌症细胞，导致过度是由肾上腺荷尔蒙皮质醇。
CIinical researchMethod: This study brings into 59 case lung cancer, through certain diagnosis by pathology or cytology, hospitalization which combine the lung cancer and large intestine cancer accepts the chemotherapy empress. lung cancer: non small cell lung cancer a plan GC(gemcitabine+ciplastin), small cell lung cancer a pl...
一、临床研究方法：本研究纳入59例，经病理或细胞学确诊并住院接受化疗后的肺癌、大肠癌，化疗采用：肺癌：NSCLC：GC方案，SCLC：CAV(环磷酰胺+阿霉素+长春新碱)方案；大肠癌：FOLFOX(奥沙利铂+亚叶酸钙+氟尿嘧啶5-FU)方案。
Methods 16 patients with SCLC received VIP regimen chemotherapy:IFO 1.5g/m2iv d1～5, Mesna 0.4g iv following IFO 0, 4 and 8h VP-16100mg iv d1～5, DDP 30mg/m2 iv d2～4 or 80～100mg/m2 d1 iv, repeated every 3～4 weeks. In patients with limited loci adjuvant chest irradiation were given following 2～3 cycles of chemotherapy.
符合治疗条件SCLC16例，给予VIP方案化疗：IFO1.5g/m2iv d1～5，IFO注射后Mesna，0.4，8小时各1次，VP-16 100mg iv d1～5，DDP 30mg/m2 iv d1～5或80～100mg/m2 iv d1，水化，每3周重复，局限期者2～3周期化疗后辅以胸部病灶野和纵隔野放疗。
Results The serum level of ProGRP3198 was significantly increased in patients with SCLC as compared to that of the normal controls as well as that in any other groups of patients.
但研究表明，NSE在局限期SCLC阳性率低，非小细胞肺癌假阳性率高，正常健康者和SCLC水平差异小，溶血标本易出现假阳性等[1]。
This treatment is now being tested in recurrent SCLC that is causing a type of airway obstruction (endobronchial obstruction, or obstruction of a bronchus from within).
这是治疗复发性小细胞肺癌，目前正在测试一种是造成呼吸道阻塞(支气管阻塞或从支气管阻塞了)。
According to the different ways acting on sample system electrically, thermally and optically, they are classified to four types, namely, SCLC, dielectric spectroscopy, TSC and photoconductivity.
以电、热、光三种对样品体系的不同作用形式就所涉及的电学测量方法进行分类，有四种方法，它们是：SCLC法、介电驰豫谱法、TSC法、光电导方法。