On the other hand, the previous studies have showed that site-directed mutagenesis identified the specific roles of the individual carbohydrate chains of FSH in signal-transducing activity and receptor-binding affinity.
另一方面，已知醣基支链对於滤泡刺激素讯息传递过程之重要性，若除去醣基之FSH α-或β-次单元体的传递活性因此而降低甚多，故醣基存在与否严重影响到FSH与其受体键结后引发的讯息传递活性。
We show that in these patients, the B-cell memory response to gp140 is composed of up to 50 independent clones expressing high affinity neutralizing antibodies to the gp120 variable loops, the CD4-binding site, the co-receptor-binding site, and to a new neutralizing epitope that is in the same region of gp120 as the CD4-binding site.
研究小组发现这些针对囊膜蛋白的抗体具有广泛的中和病毒的活性，很快研究人员将这些抗体用作研究疫苗。研究结果表明，用单一的抗体无法抵抗多变的艾滋病病毒。
RESULTS:①Westem blot of the tendons in experiment group demonstrated the up-regulation of TGF-β receptor protein levels, which mainly appeared in the tendon sheath, the epitendineum and the incision along the repair site.
肌腱损伤修复后，肌腱和腱鞘转化生长因子β1受体的表达明显增加，在术后14d达到高峰，56d开始降低，这种受体上调可能为屈指肌腱术后瘢痕形成的生物学调节提供新的途径。
The result indicates that the Mg2+ ion around the binding site is very important to stabilize the binding of the ligand to the receptor. The binding free energy estimated by the empirical function favors the system with one Mg2+ ion, in which the free energy is about 5 kcal/mol less than the system with Mg2+ ion.
含有Mg2+离子的情况下比不含Mg2+离子的体系之间的自北京工业大学工学硕士论文一由能之差为一5 kCal／m＊，结果说明结合位点处的 Mg`离子对稳定配体与受体的结合起了重要作用。
With this strategy we successfully performed the site-directed mutagenesis on an 8 kb plasmid pcDNA3.1-pIgR and recovered the wild-type amino acid sequence of human polymeric immunoglobulin receptor.
本研究用该方法成功地纠正了长约8 kb的质粒pcDNA3.1-pIgR中的突变碱基，从而获得了多聚免疫球蛋白受体的野生型氨基酸序列。
According to the prediction results of secondary structure of receptor β chain, the general theory about relationship between cytokine and its receptor at binding site and blocking results of polyclonal antiserum against D1 (9～114 residure of β chain), the new three peptides, which comprised residures of 45～75, 56～75 and 66～75, were designed and synthesized.
依据对受体β链二级结构的预测、受体与细胞因子结合部位的结构理论以及抗受体β链D1(9～114)片段多克隆抗血清有阻断GM-CSF促进DMSO诱导HL60细胞增殖活性的结果，设计和固相合成了受体β链第45～75，56～75和66～75三个人工合成多肽片段。
The scanning electron microscopic pictures of the individual particles sampled at Lukang site, showed three major types of sources. These particles were identified as sulfate, soil dust and vehicular emissions, which were similar to the results obtained by CMB receptor modeling.
鹿港大气微粒的电子显微镜照片显示，大气微粒主要有三类，分别为硫酸盐微粒、街尘与尘土及交通排放微粒，与受体模式解析结果比对，显示有类似的结果。
VWF plays an important role in primary hemostasis. vWF mediates the combination of platelet and collagen in case of endothelial injury. It also binds to the platelet membrane receptor GpIb/Ⅸ and GpⅡb/Ⅲa, creates the platelet activation signal, accelerates the platelet adhesion to the injury site and platelet aggregation which forms platelet plug. Inaddition, vWF and FⅧ form a noncovlent complex in plasma to stabilize FⅧ and prolong its half-life.
内皮细胞损伤后，vWF与内皮下胶原结合，并与血小板膜糖蛋白GpⅨ和GpⅡb/Ⅲa结合，产生血小板活化的信号，促使血小板在损伤的部位粘附，加速血小板的聚集，形成血小板血栓，此外，血浆中的vWF与FⅧ以非共价键形成复合物，起着稳定FⅧ，延长其半衰期的作用。
Previous research has shown that the S protein, which contains important virus-neutralizing epitopes and is an important target for vaccine design and development, is the bind site of SARS-CoV and host cell receptor. Targeted on S protein, it has been successful to get an effective vaccine against the coronavirus with low mutation rate in S protein.
既往对冠状病毒S蛋白的研究表明，S蛋白是SARS-CoV与宿主细胞膜受体的结合部位，包含重要的中和抗原表位，是进行抗SARS疫苗设计的重要位点。S蛋白突变率较低的冠状病毒，通过S蛋白已经获得了有效的疫苗。
In the past, the Affinity Labeling and Site-Directed Mutagenesis are the primary methods to study amine receptor.
过去主要是通过亲和标记和点突变等实验方法进行研究。
After arrival at its site of action, the first step in ABA response is expected to be some kind of perception and recognition, ABA receptor plays a key role in the signal recognition.
在ABA到达作用位点后，ABA应答反应的第一步是一系列的细胞信号感知和识别，其中，ABA受体对原初信号的识别起着关键的作用。
A noncompetitive antagonist prevents the agonist from producing any effect at a given receptor site.
非竞争性拮抗剂可阻止激动剂在特定受体部位产生任何效应。
Study of insulin receptor gene exon 8 NSI site polymorphism in aircrew metaboilc syndrome patients
飞行人员代谢综合征患者胰岛素受体第8外显子NsiⅠ位点基因多态性研究
It was concluded that the first action site of the specific toxin might be on the outside of protoplasmic membrane, moreover, the toxin receptor has the proteic characteristic and the combination between toxin and its receptor has saturation activity.
推测HT-毒素特异性组分的原始作用位点在质膜外侧，且特异性毒素组分与其受体互作具明显的饱和性。
A medicine used to treat allergies and hypersensitive reactions and colds; works by counteracting the effects of histamine on the receptor site known as H1.
用来治疗敏感症、敏感反映和伤风的药物；通过和H受点部位组胺作用相中和而起作用。
AIM: To take vitamin D receptor gene as the candidate gene for diabetic nephropathy, and investigate the correlation between vitamin D receptor gene Fok ⅰ restriction site polymorphism and the diabetic nephropathy within a Chinese population.
目的将维生素D受体基因作为糖尿病肾病候选基因，探讨维生素D受体基因FokⅠ酶切位点多态性与中国汉族人群糖尿病肾病之间的关系。
Is realized by the charge transfer complex which is formed by the transfer of electrons from receptor site to the specific hydroquinone.
取代氢醌的抗菌活性可能是通过药物与受体间的电子转移所生成的电荷转移复合物而实现的。
Study on binding site of estrogen-related receptor 1 interacting with coactivator
ERR1与核受体辅活化子相互作用位点研究
The strength of the hydrogen bond between H of NH3 + group and the 3rd receptor site of taste bud resolved in the intensity of sweetness.
氨基上的一个氢原子与甜味接受体上第3点结合形成氢键，其强度决定甜味的强弱。
Effect of Methylation at CpG Sites Upstream of Transcription Start Site of Endothelin Receptor B Gene on Migration of Neural Crest Cells
内皮素受体B基因启动子上游CpG岛甲基化对神经嵴细胞迁移的影响