Results In animal study, lumbricus could inhibit the growth of staphylococci, bacillus coli and bacillus aeruginosus. The time of wound healing in experimental group was 4 days shorter than that in control group. At 4d and 7 day the numbers of the capillary, blood vessel endodermis and desmohemoblast desmocyte and splitting epithelium of trial group were much more than those of control group. At 4d the trial group's numbers of splitting mesenchymal cell were much more than that of control group. From 3d on the wound healing and granulation filling of experimental group were much quicker than those of control group.
结果 动物实验中，地龙能抑制金黄色葡萄球菌、大肠杆菌及绿脓杆菌的生长；实验组创面愈合时间较对照组提前了4天；第4、7天实验组动物创面的毛细血管数、血管腔内皮细胞数及间质成纤维细胞数均较对照组明显增多，上皮细胞分裂象也高于对照组，第4天的间皮细胞分裂象也高于对照组；自第3天始创面愈合及肉芽充填速度实验组明显快于对照组。
Mesenchymal stem cells are multipotent stem cell, which can differentiate to the cells derived of mesoderm.
间充质干细胞是一类具有多能性的干细胞，在适宜条件下可以向多种中胚层来源的组织细胞分化。
The pupose of this study was to determine the viability of cell-based delivery of brain-derived neurotrophic factor from genetically modified mesenchymal stem cells for neuroprotection of RGC-5 cells.
本研究的目的是确定来自RGC-5细胞的神经蛋白中遗传修饰的间充质干细胞的脑源性神经营养因子进行细胞递药的可行性。
Our data showed that treatment with reveratrol inhibited cell mobility and up-regulation of the expression of E-cadherin, an epithelial marker, we also found that treatment with resveratrol down-regulating several mesenchymal markers such as fibronectin, N-cadherin and vimentin in various lung cancer cells.
实验结果显示白藜芦醇会降低上皮-间质转化相关的转录因子FOXC2的表现，也发现白藜芦醇能抑制不同肺癌细胞的移动及侵袭能力，改变上皮-间质转化相关的蛋白质表现，例如增加E-cadherin的含量，降低fibronetin、N-cadherin和vimentin的表现。
The mechanism probably is that Pishang can inhibit the growth, movement and adheresion to extracellular matrix and endothelial cell of liver tumor cells, up-regulate the expression of nm23, down-regulate the expression of CD44, MMP-2, and inhibit the tumor neovascular by supressing the vascular endothelial cell, down-regulating the expression of VEGF, damaging the primitive mesenchymal cells and inhibiting neovascular gemmation.
砒霜具有明显的抗肝癌细胞作用，并有一定的抗侵袭与转移作用，其机制可能与其能抑制肝癌细胞增殖、迁移、阻止肝癌细胞与细胞外基质和内皮细胞粘附、上调肿瘤转移抑制基因nm23表达、下调肿瘤侵袭分子CD44、MMP-2表达以及通过抑制内皮细胞增殖、下调VEGF表达、损伤间充质细胞、阻止新生血管芽生等途径从而抑制肿瘤新生血管形成有关。
Using our previously established relay culture system, a human mesenchymal stem cell-derived, human EPO-competent organoid was established in rat omentum.
采用我们先前建立的培养系统，我们在大鼠的网膜中建立了一种人类骨髓间充质干细胞来源的产人类EPO类器官。
Methods Rabbit marrow MSCs were transferred with BMP-9 gene by cationic liposome, and then were subjected to a series tests including fluorescent microscope, Flow cytometer, ALP activity quantitative assay and Von Kossa's calcium nodus staninig; MSCs transfected with BMP-9 gene successfully were seeded onto scaffolds of polylactide-co-glycolide. Cell-matrix interactions were observed with fluorescent microscopy and scanning electronic microscopy. The tissue-engineered bones with MSCs seeded on PLGA were further subcutaneously implanted into rabbits.
采用阳离子脂质体介导hBMP-9基因转染兔骨髓间充质干细胞(mesenchymal stem cells，MSCs)，荧光显微镜观察及流式细胞学检测，碱性磷酸酶活性定量测定及Von Kossa's钙结节染色；MSCs与聚乳酸－羟基乙酸(polylactide-co-glycolide，PLGA)支架共培养，荧光显微镜及扫描电镜观察MSCs在PLGA上的黏附、生长情况；将转染与未转染hBMP-9基因的MSCs分别与PLGA支架复合培养，构建组织工程化骨并回植兔肌肉内，组织植入4、8周后进行HE染色观察。
Effects of rhubarb aglycone on matrix metalloproteinase in cerebral ischemic tissue in rats with bone marrow mesenchymal stem cell transplantation.
大黄苷元对骨髓间充质干细胞移植脑缺血大鼠基质金属蛋白酶的影响。
Besides mesenchymal stem cells is the second kind of adult stem cells in marrow, which hold great promise for regenerative medicine. It is well known that MSCs is capable of self-renewal and can differentiate into many cell lineages.
20世纪60年代，Friedenstein AJ等[1]发现，体外将骨髓单个细胞贴壁培养形成集落，在不同条件下分别诱导其分化为成骨细胞、成软骨细胞、脂肪细胞和成肌细胞，这些细胞经过20个～30个培养周期，仍能保持多向分化潜能，这些细胞就是骨髓间充质干细胞(mesenchymal stem cells，MSCs)。
PDGF and TGF-β, which interplay with pulmonary mesenchymal cells, are involved in fibroplasia and deposition of extracellular matrix as well as angiogenesis and epithelial cell repopularization.
PDGF、TGF-β通过与肺组织细胞相互作用，参与成纤维细胞增殖和细胞外基质沉积，以及血管发生和上皮细胞再生。
In SMC group, relative stable of the both ends of fracture reduce unnessary repeated stimulation of injury, and at same time, axio-stress advantageous for preosteoblast and mesenchymal cell transmit to osteoblast and chondroblast. Material and design superiority of SMC form unique internal mechanical environment, and which benefit for bone healing. The study took deep investigation of SMC on fracture healing.
上述结果证实：SMC内固定可对骨折端施加主动的、持续的轴向应力刺激，形成沿长骨骨干轴向的成骨导向力值，配合环抱翼的把持作用，形成了区别于CP、IN的独特的稳定、有效的机械内环境，骨折端的相对稳定减少了不必要的损伤再刺激，同时持续轴向应力有利于成骨祖细胞、间充质细胞向成骨细胞和成软骨细胞转化、促进了成骨诱导过程的发生与发展，加快了骨折愈合的修复与重建。
79780 Effects of autologous bone marrow mesenchymal stem cell transplantation on angiogenesis in rabbit ischemic limbs: A high-frequency ultrasound evaluation
朱栋晓，苗宗宁，赵基栋，钱寒光，刘小铭高频超声评价自体骨髓间充质干细胞移植对兔缺血肢体血管再生的影响
Objective:The purpose of this research is to observe the influence of nourish kidney on that rat bone marrow mesenchymal cells forming liver cells, and to study the mechanisms of that nourishing kidney manufacture marrow to form liver cell, and then to establish experiment foundation for the study of promoting differentiation from bone marrow cells into liver cells and provide scientific evidence for its clinical application.
目的：研究左归丸含药血清对骨髓间质细胞分化为肝细胞的影响，探讨中医补肾生髓成肝的机制，为促进骨髓干细胞向肝细胞分化的研究奠定实验基础，为补肾治疗肝病的临床应用提供科学依据。
All the above tumor cells are originated from the multipotential primitive mesenchymal cell.
各型瘤细胞的组织发生均来源于多能性原始间叶细胞。
These include immortalized stem cell lines, neural progenitors prepared from embryonic and adult animals and mesenchymal stem cells.
这些措施包括永生化的胚胎干细胞，来源于胚胎的和成年动物的神经祖细胞以及间充质干细胞。
Therapeutic effect of mesenchymal stem cell on diabetes in rats YANG Bailiang, GUO Li, REN Shuping, et al.
作者：杨柏梁1，郭丽2，任淑萍2，张桂英3，李鹏2，肖博晗4，刘雅娟3 作者单位：吉林省卫生厅医学科研基金项目([2003]13) 1。
This study was aimed to compare K562 cell proliferation, cell cycle and apoptosis before and after adhesive culture with MSCs of the same and different counts, so as to investigate the effect of human bone marrow mesenchymal stem cells on the growth of K562 cells.
本研究比较K562细胞与相同数量以及不同数量的人骨髓间充质干细胞黏附培养前后K562细胞增殖、细胞周期和凋亡的变化，以探讨MSC对人白血病K562细胞生长的影响。
Content of mesenchymal cells in the cell-suspension was detected by flow cytometric analysis, and limbal stroma surface was examined by scanning electron microscope to assess cell-suspension method.
采用流式细胞技术分析分离的角膜缘上皮细胞悬液中间质细胞的含量，采用扫描电镜观察去除上皮的角膜缘基质表面。
Content of mesenchymal cells in the cell-suspension was deteeted by flow cytometrie analysis, and limbal stroma surface was examined by scanning electron microscope to assess cell-suspension method.
采用流式细胞技术分析分离的角膜缘上皮细胞悬液中间质细胞的含量，采用扫描电镜观察去除上皮的角膜缘基质表面。
Dermal fibroblasts were co-cultured with bone marrow-derived mesenchymal stem cells grown in inserts, which allowed for paracrine interactions without direct cell contact.
我们通过真皮成纤维细胞和骨髓间充质干细胞共培养发现骨髓间充质干细胞可以调节真皮成纤维细胞的增值，迁移和基因表达。