Different total doses can be obtained through the repeated and overlapped exposure without changing every dose in the method. Also, the scanning method does not need the complex division of patterns, so the data is decreased, and the data transmission time is shorted, the total exposure time is reduced, the exposure efficiency is improved. The beam parameters need not be changed, which gets over the limit of inner frequency and provides favorable condition for curvilinear microstructure.2. The calculation method of relation between the dose and depth is proposed according to the experiential formula of resist contrast. The calculation not only reduces experimental time and measurement error, but also provides significant parameters for 3D microfabrication.3. The calculation methods of resist sensitivity and contrast are respectively proposed, which provides important parameters for EBL and calculation of relation between the dose and depth.
重复增量扫描方式无需改变曝光剂量，通过重复、重叠的多次曝光，使光刻图形不同的位置得到不同的曝光总剂量，实现对图形的三维加工；该扫描方式也无需进行复杂的图形分割，避免了图形分割带来的数据量过大的问题，降低了数据传输时间，从而可以降低曝光总时间，提高曝光效率；该扫描方式也不用在光刻过程中改变束斑参数，克服了系统内部扫描频率的限制，为通用电子束光刻系统进行曲面图形的加工提供了条件。2、根据光刻胶的反差的经验公式，提出了曝光剂量与刻蚀深度关系的计算方法，减少了实验次数和由于测量带来的误差，而且为电子束光刻的三维加工提供了重要参数。3、提出了抗蚀剂灵敏度、反差的计算方法，为电子束三维加工和曝光剂量与刻蚀深度关系的计算提供了重要参数。
In different tissues such as heart, lung, muscle were determined resp. at 0.25, 0.50, 1.00, 2.00, 4.00h after administration. The gatifloxacin had good linear relation over the range from 0.05 to 5.00μg/ml, with a detection limit of 0.05μg/ml. The pharmacodynamics process of rabbits fitted to one compartment model. The main kinetic parameters for the dose groups at 5, 10, and 20 mg/kg were follows: C were 2.28, 3.35 and 7.93μg/ml reap. T were 1.36, 1.83 and 1.69 h reape.; t(subscript 1/2) Ka were 0.39, 0.51 and 0.42 h reap.; t(subscript 1/2)Ke were 5.63, 6.07 and 6.81 h reap.; AUC were 21.67, 33.59 and 97.07/ml reap.
结果］加替沙星在0.05~5.00μg/ml范围内具有良好线性关系，最低检测限为0.05μg/ml，在家兔血液代谢动力学过程符合一室模型。5、10和20mg/kg剂量组主要动力学参数如下：峰浓度C(下标 max分别为2.28、3.35和7.93μg/ml；达峰时间T(下标 max分别为1.36、183和1.69h；吸收半衰期t(下标 1/2Ka分别为0.39、0.51和0.42h；消除半衰期t(下标 1/2Ke分别为5.63、6.07和6.81h；药时曲线下面积分别为21.67、3359和97.07/ml。
In the method, the polyclonal antibodies are obtained by utilizing syntactic quinoxalone antibiotics multi-cluster antigen immunization; the coupling compound of the half antigen of the quinoxalone antibiotics and an egg-white protein OVA is taken as an envelope antigen; the quinoxalone antibiotics is taken as a standard; the indirect competitive enzyme-linked immune detection method for the quinoxalone antibiotics in animal food is established; a rapid and high efficient detection means is provided for the residues of the quinoxalone antibiotics in the animal food; because the polyclonal antibodies are adopted, the cost is low, and the stability and the repeatability are good; the detection limit (IC is smaller than 90) is 0.0126 ng/ml, the median inhibitory dose (IC is smaller than 50) is 0.52 ng/ml, and the detection range (IC is smaller than 20 to 80) is 0.04467 to 14 ng/ml.
本发明利用合成的喹诺酮类抗生素多簇抗原免疫得到多克隆抗体，以喹诺酮类抗生素半抗原与卵清蛋白OVA的偶联物作为包被抗原，以喹诺酮类抗生素为标准品，建立动物性食品中的喹诺酮类抗生素的间接竞争酶联免疫检测方法；为喹诺酮类抗生素在动物性食品中的残留检测提供了快速高效的检测手段，由于采用的是多克隆抗体，费用较低并且稳定性和重复性较好，检测限(IC 90)为0.0126ng/ml、半数抑制量(IC 50)为0.54ng/ml和检测范围(IC 20 ～IC 80)为0.04467～14ng/ml。
Methods The parameters including culture temperature, limit of detection of penicillin and the maximum tolerance dose of experimental strain ATCC9341a to streptomycin sulfate were detected by cylinderplate method.
利用抗生素在琼脂培养基内的扩散作用，采用管碟法对培养温度、青霉素的最低检测限及试验用菌种ATCC941a对硫酸链霉素的最大耐受量等条件进行研究。
Methods The parameters including culture temperature, limit of detection of penicillin and the maximum tolerance dose of experimental strain ATCC9341a to streptomycin sulfate were detected by cylinder? plate method.
利用抗生素在琼脂培养基内的扩散作用，采用管碟法对培养温度、青霉素的最低检测限及试验用菌种ATCC941a对硫酸链霉素的最大耐受量等条件进行研究。
The lifetime dose of radioactivity to which a person eating irradiated food could be exposed could realistically amount to one- millionth of the recognised limit of average exposure of an individual to radioactivity from other source over the same period.
人们由于吃进辐照食物所遭受的放射剂量，实际上不多于同一时期一个人平均可能遭受到的来自其它放射源的放射的可觉察的极限的百万份之一。到中国译典经典版本中查找关于millionth的最新解释和例句。。。。
The ELISA titre was 1:2000.By cell fusion, 46 hybridoma cell lines were screened, and 10 lines were cloned with limited dilution method.16 lines secreting anti-bFGF monoclonal antibody were been developed, and 2 lines targeted fusion protein. Sensitive ELISA and dot-ELISA for bFGF was developed with this mAb. The detection limit of them were 0.1 ng/well and 0.5 ng/well. The expression level of anti-bFGF mAb by different rebuilt engineering cells were identified by western blot and to direct rebuild recombiment engineering cell. The dose and character of anti-bFGF mAb inhibiting bFGF biology activity were searched by 3T3 cell line. Searching 20 tissue of liver cancer, liver cancer cell lines and general tissue of liver, finding bFGF were highly expressed in tissues of liver cancer and liver cancer cell lines. Affinity chromatography purifying bFGF was set up by mAb binging CNBr-pepharose 4B, and the purification was 95%. We found that the titer of anti-bFGF antibody was very high in serum of neuropathic amyotrophia.
应用细胞融合制备46株杂交瘤，对其中10株进行克隆化，获得bFGF特异单抗16株，2株针对融合蛋白；应用该单抗建立了0.1ng/孔灵敏度的ELISA，0.5ng/孔敏度的斑点ELISA；用Western-blotting鉴别了经改造不同工程菌蛋白表达，指导重组工程菌改造；用3T3细胞培养研究了单抗抑制bFGF生物学活性的剂量和特点；合作研究了20例肝癌、肝癌细胞株和正常肝组织，发现前者bFGF高表达；应用单抗偶联CNBr-sepharose 4B建立了小量免疫亲和层析纯化bFGF，纯度达到95%；发现神经性肌萎缩患者血清中含有高滴度的bFGF抗体，已有10多家单位引用单抗或进行合作。
CS-055 is relatively rapid absorption rate, but the increase is below the AUC dose increased, suggesting that there may be absorbed by the saturation dose limit trends.
CS—055吸收速度相对比较迅速，但AUC的增加均低于给药剂量的增加，提示吸收可能存在受剂量限制的饱和趋势。
Methods: In a randomized crossover design, 20 healthy male volunteers were given a single oral dose of 1mg test or reference Ribaviri granules. The concentrations of Ribaviri in human plasma were determined by a HPLC-MS method and the main pharmacokinetic parameters were analyzed by BAPP 3.0. Results: The calibration curve of Ribaviri was linear in the range of the concentration range of 9.40 ～ 1410 ng/ml and the detection limit was 9.40 ng/ml.
20名健康男性志愿者按照两制剂两周期的随机交叉试验设计，分别单剂量口服参比制剂（四川百利药业有限责任公司生产的利巴韦林颗粒剂）和受试制剂（郑州康立制药有限公司生产的利巴韦林颗粒剂），剂量均为300 mg，采用液相色谱-质谱法测定人血浆中恩替卡韦的浓度，用BAPP 3.0软件计算各药代动力学参数，并进行生物等效性统计分析。
SiGe SIMOX: Oxygen ions with high dose were implanted into SiGe grown directly on silicon substrate for the first time, and SiGe-OI novel structure was formed successfully with additional high temperature annealing; It has been confirmed that Oxygen implantation with 45keV, 31017cm-2 and annealing at 12500C in Ar + 5% O2 for 5 hours, are fit for the formation of SiGe-OI structure; Ge loss during the high temperature annealing has been observed, which is originated from Ge volatility and Ge diffusion; It has been proposed to use nanoporous layer induced by H+/He+ implantation to surppress Ge diffusion and to use surface oxidation to overcome the upper limit of SiGe SIMOX.
纽鲤里上上四山凶j叠上纺匹L在SIGe材料中注入剂量为6 X10`飞m－`的H离子，经过高温处理，实验中现察到450`C以上的热处理可以在 SIGe表面形成气泡和剥离坑，从而证实了通过智能剥离技术实现 SIGe层转移的可行性；通过对比 600忙处理下 SIGe和引表面形成的气泡和剥离坑的不同，得出SIGe材料比St中更容易形成气泡层和剥离，困而更易于实现层转移；分析指出这一差异的原困可能是SIGe层中存在的应变和SIGe和St中键能的差异。
The normal public dose limit in the US, and recognized around much of the world, is 100 millirems per year.
一般公共剂量限值在美国，和公认的周围世界许多地方，是100 millirems每年。
Because of the time limit, we investigated the bipolar plate voltage of electrolyzer only. The result shows that the time and the dose of sulfonating agent are key factors of controlling the bipolar plate voltage of electrolyzer.
由于时间仓促，仅对电解槽两极板间电压进行实验，结果表明磺化时间以及实验中磺化剂的用量都是控制电解槽两极板间电压的主要因素。
The calculation of DWC is based on the ALI of waterand limit of annual effective dose equivalent for the public....
DWC的计算是基于公众的年摄入量限值和年有效剂量当量限值。给出了计算的导出水浓度。
Results For 32 cases, the absolute dose value at the isocenter was below the tolerance limit of 5%; for one case, the dose value exceeded the range, but re-meet the demand through adjusting the measure point to a flat region of dose distribution.
结果所有患者的调强计划验证结果中有32例等中心点剂量误差在5%内符合，1例超出标准则重新选取两处剂量变化较缓区域补测点剂量，结果亦在5%内符合；
The biggest dose equivalent that maintenance workers accepted per year is only equal to 1/2~1/3 of the dose limit value which state stipulated.
后二种型号料位计对维修人员年最大接受剂量当量，只有国家剂量限值的1／2～1／3。
(Conclusion) Intramuscular rocuronium, 2 mg/kg, can provide good-excellent (intubation) condition within 4 to 6 min and long duration of action about 2 h. Duration of action of large dose rocuronium might limit clinical utility.
结论婴幼儿肌注罗库溴铵2mg/kg能在4~6min内提供优良的插管条件，但临床肌松作用长达2h以上。
According to the change of occupational exposure dose limit for workers, as well as actual circumstances in China, radon and daughter concentration limit in the underground uranium mine and the parameter to be chosen were discussed in this paper.
依据工作人员职业照射剂量限值的变化，结合我国实际情况，对铀矿井下空气中氡及氡子体浓度管理限值的确定及其参数选择进行了探讨。
Radiation sickness (or acute radiation syndrome) usually sets in after a whole-body dose of three sieverts & 3, 000 times the recommended public dose limit per year, Langhorst says.
Langhorst说，辐射疾病（或急性辐射综合征）通常发生于全身辐射水平超过3000毫希以上，为每年公众允许辐射上限的3000倍。
And found two data limit of accumulative radiation dose: R1 and R2. When accumulative radiation dose is smaller or near R1, the attenuation rate of ρ, ε, P is the same as it of natural ageing.
还发现对于此复合材料存在两个累积辐射剂量的数值界限R1和R2。当累积辐射剂量小于或接近R1时，复合材料的ρ、ε、P和τ的变化趋势与自然老化规律基本相同；
Results The results showed that radioactive levels of granites were much higher and their extra values of annual effective equivalent dose of internal radiation to residents exceeded the national standard limit of 1 mSv, and only 47% of granites seemed to be suitable for room decoration;
结果花岗岩放射性水平较高，其致居民内照射年有效剂量当量附加值已超1mSv的国家标准限值，仅有47%的品种可用于室内装饰；