Dip-pen nanolithography is a new kind of scanning probe lithography technique based on atomic force microscopy, and now has made a great progress.
中文摘要：蘸水笔刻蚀（dip-pen nanolithography ，DPN）技术是近年来发展起来的基于原子力显微镜的一种扫描探针加工技术，有着广泛的应用前景。
The paper detailed analyzed the mechanism of this technique, integrated introduced the latest development, including electrochemical DPN, more-mode DPN, multiple DPN, multi-probe array DPN and so on. Finally, the paper described the characteristics and its application.
文章具体分析了蘸水笔技术在不同阶段的作用机理，综合介绍了蘸水笔刻蚀技术在近年来的进展，包括电化学DPN 技术、DPN 的多种加工模式、DPN 的复合加工及多探针的DPN 加工等；分析了DPN的加工特点及其应用。
Secondly, by utilizing Dip-Pen Nanolithography, protein and antibody have been first directly written onto Au substrate through reasonable design.
通过合理的超分子相互作用的设计，利用DPN技术将针尖上的蛋白质分子、抗体分子直接书写到镀金的云母基底上，得到了尺寸、形状和位置均精确可控的生物材料纳米图形，为纳米生物器件的制造提供了一个简单的、低成本的、崭新的办法。
And such nano-assembly structure was studied as SERS substrate. Secondly, by utilizing Dip-Pen Nanolithography, proteinand antibody have been first directly written onto Au substratethrough reasonable design.
通过合理的超分子相互作用的设计，利用 DPN 技术将针尖上的蛋白质分子、抗体分子直接书写到镀金的云母基底上，得到了尺寸、形状和位置均精确可控的生物材料纳米图形，为纳米生物器件的制造提供了一个简单的、低成本的、崭新的办法。
Nitric oxide in the brain and amygdala are involved in the inhibitory effect of somatic afferent input on central pressor response.
中枢NO参与DPN传入冲动对PVN中枢性心血管反应的抑制作用，其机制与杏仁有关。
The results indicate that during the baroreflex resetting induced by DPN stimulation, there were an upward shift of the ISP-GNA and ISP-CVD response curves, an upward displacement of the ISP-RNA, ISP-SPNA and ISP-CNA response curves at low ISP range while a downward displacement of these curves at high ISP range, a downward shift of the ISP-DPD response curve at high ISP, and no significant alteration in the ISP-LNA, ISP- SPD response curves.
结果表明，在刺激DPN引起压力感受性反射重调定时，窦内压-颈交感神经放电反应曲线和窦内压-颈迷走传出单纤维放电反应曲线上移；窦内压-肾交感，窦内压-内脏交感以及窦内压-心交感放电反应曲线的低ISP部分有所上移，而高ISP部分有所下移；窦内压-腰交感神经干放电反应曲线以及窦内压-腓浅神经交感单纤维放电反应曲线无明显改变；窦内压-腓深神经交感单纤维放电反应曲线的高ISP部分有所下移。
The bacterial strain, MBM7070 F〓 lacZ (Am CA7070, lacY1 hsdR hsdM 7679 galH galk rpsc thi was transformed with Dpn1 treated plasmid DNA by the calcium chloride procedure and transformants were placed on Luria Broth plates containing ampicillin, X-gal (5-bromo-4-chloro-3-indoyl-β-D-galactoside) and IPTG (isopropyl-β-D-thiogalactoside).
然后用CaCl〓法将从细胞中提纯的质粒转化受体菌MBM7070F〓lacZ(AmCA70070，LacY1 hsdR hsdM7679 galH galK rpsc thi，将转化子细菌置于含氨苄青霉素、5-溴-4-氯-3-吲哚基-β-D-半乳糖苷(5-bromo-4-chloro-3-indoyl-β-D-galactoside，X-gal)以及异丙基-β-D-硫代半乳糖苷(isopropyl-β-D-thiogal-actoside，IPTG)的LB平板中。
In the 30 patients of diabetes mellitus without neuropathy, there were 8 patients with prolonged duration of F wave, 4 prolonged minimum latency of F wave, 2 increased ratio of the area of F/M.
有神经病变的 DM患者 76例，F波最短潜伏期均延长； F/M波波幅和 F/M波面积增大； F波时限在轻型 DPN患者中增宽，在重型 DPN患者中未见明显异常。
Results The minimum latency prolonged and ratio of amplitude of F/M and the ratio of the area of F/M significantly increased in the patients with DPN, the duration of F wave prolonged in the mild DPN but revealed normal in the severe ones.
结果无神经病变的 DM患者 30例，F波时限增宽 8例，F波最短潜伏期延长 4例，F/M波面积增大 2例。
Pregabalin was safe and effective in decreasing pain associated with DPN, and also improved mood, sleep disturbance, and quality of life.
普瑞巴林对减轻DPN疼痛是安全、有效的，并且还能改善患者情绪、睡眠障碍和生活质量。
As a member of schneider electric, sslvta is focusing on the manufacture of modulus low voltage terminal electric products, including 1p+n miniature circuit breakers, residual current circuit breaker with vigi modules, residual current circuit breaker with over-voltage function, int isolator, vigi c45/c63 earth leakage protection auxiliary, vigi c65 earth leakage protection auxiliary, anjia series, mini-pragma enclosure, etc.
作为施耐德电气的一员，公司致力于生产专业化的模数低压终端电器产品，主要产品有dpn带中线小型断路器、dpn vigi漏电保护断路器、dpn vigi g漏电过压保护断路器、int隔离开关、vigi c45/c63漏电保护附件、vigi c65漏电保护附件、安家系列产品（ajr、ajd、ajv、aji）和mini-pragma小康家等。
It was found that the integrated responses depended on the time intervals to the stimulation of both nerves. Although the effect of the stimulation of DPN and SPN alone on a RVLM neurone was all excitation; the precedent stimulation of DPN with different time could augment or weaken the excitatory effect of SPN on the same neurone, indicating that RVLM neurones integrate impulses from different somatic nerves was also according to the nature of impulses and the arrival time of them.
尽管单独刺激DPN和SPN对RVLM神经元的作用都是兴奋，但用不同的时间间隔刺激DPN和SPN，DPN对SPN的兴奋作用可以加强，也可以减弱；说明RVLM神经元对来自躯体神经的信息不是简单相加，也是根据信息的性质和到达时间进行整合。
The radioiodinated 7α-O-iodoallyl diprenorphine (7α-O-IA-DPN) as a new opioid receptor imaging agent for SPECT study is developed. The design and radiochemical synthesis of 7α-O-IA-DPN labeled with iodine-125 are performed. In vitro and in vivo opioid receptor binding assays, and in vitro stability are studied, respectively.
研制了一种适合单光子发射计算机断层显像用的阿片受体配基碘烷特培洛菲(7α O IA DPN)，合成了阿片受体显像剂125I 7α O IA DPN，并检测了标记物的体外稳定性，进行了体内外结合实验研究。
Duloxetine appears to be less cardiotoxic and is licensed in the US and EU for alleviating DPN.
度洛西汀似乎心脏毒性较小，已在美国和欧洲获得使用许可用于治疗DPN。
Duloxetine appears to be less cardiotoxic and is licensed in the US and EU for alleiating DPN.
度洛西汀似乎心脏毒性较小，已在美国和欧洲获得使用许可用于治疗DPN。
The drainpipe networks geographical information system which abbreviates as DPN-GIS is an application developed with the Mapobjects of ESRI and Visual Basic Language in the VB programming environment.
本文中开发的排水管网地理信息系统是利用美国环境系统研究所的MapObjects组件和Visual Basic语言在VB平台上开发出来的应用程序。
Methods 160 patients with DPN for 1 to 39 years were divided into two groups at random: 80 cases with peripheral neuropathy for 1month to 20 years in therapy group, 52 males, 28 females, aged 60- 86, treated with prostaglangin E120 μ g/d plus 250 mL saline and Danshen 20 mL/d plus 250 mL saline intravenousdrip; 80 cases with peripheral neuropathy for 1month to 19 years as controls only treated with Danshen 20 mL/d plus 250 mL saline intravenousdrip.
160例老年 2型糖尿病周围神经病变患者随机分为 2组，观察组 80例，每日给予丹参注射液 20 mL加生理盐水 250 mL静脉点滴，前列腺素 E1 20 μ g加入生理盐水 250 mL静脉滴注。
METHODS: Sixty DPN patients were randomly divided into 2 groups (n=30). Besides the general treatments such as hypoglycemics and hypotensives, therapy group received intramuscular injection (1/d) of 20 mg cyntridini triphosphatis solved in 2 mL normal saline, and control group were treated with placebo instead, with 20 d as a course.
将60例2型DPN患者随机分为2组，在常规降糖、降压等治疗基础上，治疗组30例采用注射用磷酸胞尿苷二钠20 mg加入生理盐水2 mL中溶解肌肉注射，1次/d；对照组30例采用安慰剂，以21 d为一个疗程。
The changes in their symptoms and signs were recorded, and the motor and sensory nerve conduction velocities of median nerve and common peroneal nerve were detected with electromyography before and after treatment.
通过肌电图仪测定两组患者治疗前后主侧肢体的正中神经、腓总神经的运动传导速度和感觉传导速度，并记录临床症状、体征变化，从而观察磷酸胞尿苷二钠治疗2型DPN的疗效。
Further studies are necessary to clarify the best combination of treatment for DPN.
因此需要进一步的研究以阐明治疗DPN的最佳组合。