Target blood drug concentration of group B was set as 0.5μg/ml, patients ingroup C was given loading dose by intravenous infusion in the range of 0.5 or1.0mg/kg (Anesthesia not regain consciousness without the patients agitation dose of0.5mg/kg, Other patients a dose of 10mg/kg.).The induction time of both groups was1 minute. Ramsay Scale was recorded every 1 hour.
B组起始目标血药浓度0.5μg／ml，C组首先静脉推注负荷剂量0.5或1.0mg／kg(全麻未醒无躁动者用0.5 mg／kg，余用1.0mg／kg)，诱导时间均为1分钟，两组均每小时进行Ramsay评分，B组以0.5～2.0μg／ml为目标血药浓度维持目标镇静深度(Ramsay镇静评分2～5分)；C组以0.5～2mg／kg／h的输注速度维持同样的目标镇静深度。
Results The respiratory motion influenced the actual dose of target. When the respiratory motion range increased, the area of dose was more extensive, the max dose of the target was lower. The respiratory motion was smaller than half height-width, the shape of higher dose was ellipse and the direction of short axis was the same as that of respiratory motion. The respiratory motion was bigger than half height-width, the area of higher dose became longer and the direction of ellipse long axis was same as the respiratory motion. When the respiratory motion range increased, the value of Fv was bigger.
结果：呼吸运动对靶区实际剂量分布有影响；呼吸运动幅度越大，剂量分布面积越大，射野最大剂量值越小；运动幅度小于射野半高宽时，高剂量区为椭圆形，且椭圆的短轴方向与运动方向相同；当运动幅度大于射野半高宽时，高剂量区被拉长，变为椭圆的长轴方向与运动方向相同；呼吸运动幅度越大，F值越大。
In different tissues such as heart, lung, muscle were determined resp. at 0.25, 0.50, 1.00, 2.00, 4.00h after administration. The gatifloxacin had good linear relation over the range from 0.05 to 5.00μg/ml, with a detection limit of 0.05μg/ml. The pharmacodynamics process of rabbits fitted to one compartment model. The main kinetic parameters for the dose groups at 5, 10, and 20 mg/kg were follows: C were 2.28, 3.35 and 7.93μg/ml reap. T were 1.36, 1.83 and 1.69 h reape.; t(subscript 1/2) Ka were 0.39, 0.51 and 0.42 h reap.; t(subscript 1/2)Ke were 5.63, 6.07 and 6.81 h reap.; AUC were 21.67, 33.59 and 97.07/ml reap.
结果］加替沙星在0.05~5.00μg/ml范围内具有良好线性关系，最低检测限为0.05μg/ml，在家兔血液代谢动力学过程符合一室模型。5、10和20mg/kg剂量组主要动力学参数如下：峰浓度C(下标 max分别为2.28、3.35和7.93μg/ml；达峰时间T(下标 max分别为1.36、183和1.69h；吸收半衰期t(下标 1/2Ka分别为0.39、0.51和0.42h；消除半衰期t(下标 1/2Ke分别为5.63、6.07和6.81h；药时曲线下面积分别为21.67、3359和97.07/ml。
objectiveto investigate the effects of intense pulse light on the cell proliferation and cell cycle of human fibroblasts and to provide the possible theoritical basis for the treatment of face-lift. methodscultured human skin fibroblasts and treated with different dose of intense pulse light radiation. by culturing 24 hours analyzed cell cycle with flow cytometr, the cell proliferation activity was measured by mtt assay. resulstsresults showed both proportion of cells in s and g2m phase was increased and that of g1 was decreased when the cells were irradiate with ipl in comparison with non- irradiate significantly, pri were beyond its normal range. conclusionintense pulse light radiation could promote the cell proliferation and synthesis of dna in cultured primary fibroblasts.
目的：研究强脉冲光对正常离体人皮肤成纤维细胞（fibroblast，fb）的生长活力、细胞增殖能力以及细胞周期变化的影响并探讨其可能的发生机制，为强脉冲光除皱提供可能的理论依据。方法：培养人皮肤成纤维细胞，应用mtt比色法、免疫组织化学的方法和流式细胞仪分析技术，观察皮肤成纤维细胞经不同能量的强脉冲光照射后细胞的生长活力、细胞增殖能力以及细胞周期变化。结果：强脉冲光能促进体外培养人皮肤成纤维细胞增殖，fcn结果显示强脉冲光照射后，成纤维细胞g1期百分比降低，而s期百分比升高，增殖指数pri值（s+g2m）百分比增高。结论：强脉冲光可促进正常成纤维细胞增殖和dna合成，从而为强脉冲光面部美容除皱供理论依据。
In this observational study, 65 children were treated with SLIT with a build-up phase of 11 days, culminating in a peak dose of 300 IR, and followed by a maintenance phase of 300 IR three times weekly. There were 51 boys and 14 girls; age range was 38 to 80 months (median age, 60 months). Allergens used were house dust mites in 42 patients, grass pollen in 11, olive pollen in five, Parietaria pollen in four, and cypress pollen in three patients. Adverse reactions and changes in the treatment schedule were compared in children aged 38 to 60 months vs those aged 61 to 80 months.
在这项观察性试验中，65位接受SLIT的儿童在11天的适应期后，将剂量逐渐调整到最高300 IR，接著以每周3次，每次300 IR的剂量持续接受治疗；试验中包括51位男童与14位女孩，年龄介于38至80个月（平均年龄为60个月）；其中有42位病患以尘蹒、11位以花粉、5位以橄榄花粉、4位以墙草、3位以丝柏作为过敏原；年龄介于38至60个月的儿童，与61至80个月的儿童分成两组比较不良反应发生机率与治疗疗程的改变。
Although both 7Li ion beams and γ-rays could stimulate the seed germination within a certain range of doses, the seedling formation and survival germination responded differently to these two mutagens. The seedling formation was obviously promoted by 7Li ion beam treatment at the dose of 109 ions/cm2. With the increase of the dose of 7Li ion beams, the growth and development of euphylla progressed slower and the survival germination decreased obviously.
二者虽然在一定剂量范围都能够促进种子萌发，但对种子成苗的影响依诱变源和剂量不同而有所不同。7Li 1 0 9ions cm2 处理对幼苗形成有明显促进作用，随着7Li离子束剂量升高，幼苗生长受到一定程度的抑制，真叶的生长发育迟缓，成苗率明显下降。
Though we have explored three examples with different dose of rapamycin, still it is necessary to have further exploring on the exact protective concentration range.
想表达的中文意思：虽然本实验探讨了三个不同剂量的雷帕霉素的作用效果，但是还有必要进一步探讨雷帕霉素起保护作用的确切的范围。
Although we have explored three different dose of rapamycin used before ischemia, there are still need to test an exact protective concentration range.
想表达的中文意思：虽然本实验探讨了三个不同剂量的雷帕霉素的作用效果，但是还有必要进一步探讨雷帕霉素起保护作用的确切的范围。
Objective To determine the best suitable maintenance dose of warfarin and normalize warfarin application in pulmonary thromboembolism that can make international normalized ratio achieve therapeutic range (2 to 3 times the control) promptly.
目的 探讨华法令抗凝治疗肺血栓栓塞症时尽快达到国际标准化比值在2~3之间时的剂量及方法。
In the method, the polyclonal antibodies are obtained by utilizing syntactic quinoxalone antibiotics multi-cluster antigen immunization; the coupling compound of the half antigen of the quinoxalone antibiotics and an egg-white protein OVA is taken as an envelope antigen; the quinoxalone antibiotics is taken as a standard; the indirect competitive enzyme-linked immune detection method for the quinoxalone antibiotics in animal food is established; a rapid and high efficient detection means is provided for the residues of the quinoxalone antibiotics in the animal food; because the polyclonal antibodies are adopted, the cost is low, and the stability and the repeatability are good; the detection limit (IC is smaller than 90) is 0.0126 ng/ml, the median inhibitory dose (IC is smaller than 50) is 0.52 ng/ml, and the detection range (IC is smaller than 20 to 80) is 0.04467 to 14 ng/ml.
本发明利用合成的喹诺酮类抗生素多簇抗原免疫得到多克隆抗体，以喹诺酮类抗生素半抗原与卵清蛋白OVA的偶联物作为包被抗原，以喹诺酮类抗生素为标准品，建立动物性食品中的喹诺酮类抗生素的间接竞争酶联免疫检测方法；为喹诺酮类抗生素在动物性食品中的残留检测提供了快速高效的检测手段，由于采用的是多克隆抗体，费用较低并且稳定性和重复性较好，检测限(IC 90)为0.0126ng/ml、半数抑制量(IC 50)为0.54ng/ml和检测范围(IC 20 ～IC 80)为0.04467～14ng/ml。
The sensitive Cesium Iodide scintillation crystal of the GammaRAE II R provides a fast, two-second response to radiological threats, while the energy-compensated PIN diode provides high dose rate range coverage and accurate dose measurements.
其高灵敏度碘化铯闪烁晶体可确保该仪器在2秒内迅速对放射性威胁作出响应。而具有能量补偿功能的PIN二极管可在高剂量率范围内作出响应并记录累积剂量值。
Methods We used Amphotericin B for fungous septicemia complicated with allo-geneic hematopoietic stem cell transplantation (2 cases of server aplastic anemia, 1 case of acute lymphoblastic leukemia) or chemotherapy (2 cases of chronic lymphoblastic leukemia, 5 cases of acute monoblastic leukemia). The long-term of one to three months Amphotericin B was used at total dose range from 1750 to 3115 microgram with drug prophylaxis and care.
对异基因造血干细胞移植3例（SAA 2例、ALL 1 例）和白血病化疗后7例（CLL 2例、M55例），出现真菌性败血症时应用长程（1～3个月）的两性霉素B治疗，总剂量为1750～3115 mg，观察其疗效和并发症，且对并发症采用药物预防和护理。
Results when all other parameters kept unchanged, the tube voltage was direct proportional to ctdi, the tube current was positive linear correlation to ctdi, the diameter of phantom was inverse proportional to ctdi, radiation dose of ct was decreasing while measuring depth increased of inside phantom, pitch was inverse proportional to accumulated dose, overexposure from spiral scanning out of topogram range led to the increasing of radiation dose, collimation was inverse proportional to ctdi, ctdi was not affected by field of view and algorithm, and radiation dose of ct was decreased by using tube current modulation technology.
结果 当其它参数一定时，管电压与ct剂量成正比；管电流与ct剂量成线性正相关；模体直径与ct剂量成反比；ct剂量随模体内径向深度的增加而减少；螺距与剂量成反比，螺距的增加使超成像范围的剂量增加；准直宽度与剂量成反比；照射野和算法对ct剂量没有影响；采用管电流调制技术可降低ct剂量。
There was no bad effect on the nutrient of gelatin in the range of moderate irradiation dose, and the total amount of 18 kinds of amino acids in ir- radiated gelatin increased little compared with that of unirradiated.
明胶是以动物皮、骨等加工而成的淡黄色半透明物质，富有营养，蛋白质含量达90%以上，含有18种氨基酸，广泛用于食品、医药和照相材料等工业领域。
MATERIALS AND METHODS: Different concentrations of SOFC were co-incubated with human embryo lung diploid cells. The degree of malignant transformation was observed by assessing the biological characteristics of the cells. RESULTS: The concentration of SOFC within the dose range of the experiment (25~400μg/ml) could induce malignant transformation of the human embryo lung diploid cell, and with an obvious dose-response relationship.
材料与方法：以胡麻油烟凝聚物作为受试物染毒人胚肺二倍体细胞，建立体外恶性转化实验系统，对转化细胞进行ConA凝集实验、软琼脂培养实验以及裸鼠休内致瘤实验，观察井检测细胞是否发生恶性变。
If the range of actual dose of virus used for challenge was defined in the national quality standards of animal biological products, the results would be more re...
建议在新版《中华人民共和国兽用生物制品质量标准》中增加对病毒攻毒实际剂量范围的规定，以使结果的判定更为合理。
It uses flat panel detector to receive X-ray and transforms X-ray to digital image signals directly with many significnt advantages such as high image resolution, wide dynamic range, fast imaging speed and low-dose exposure on the human body. Now DR is one of the most advanced medical imaging methods, and used in clinical diagnosis more widely.
数字化X线摄影成像(Digital Radiography，DR)利用平板探测器接收X射线，直接获得数字图像信号，具有图像分辨率高、动态范围宽，成像速度快，对人体辐射小等显著优点，成为当今X线摄影领域最先进的医学成像方法，在临床诊断和科学研究中都得到了越来越广泛的应用。
The delay before administrationof the first dose of codeine was not statistically differentbetween groups: 45 min (20–2880) vs 30 min (10–2880), median and range for the block and morphine group, respectively.
可待因首剂量注射前的滞时在两组间也无统计学差异：阻滞组和吗啡组的中位数和范围分别为45 分钟(20–2880)比30 分钟(10–2880)。
The radiation doses were in the range of 3500 to 10000 cGy, with an average dose of 6560 cGy.
手术采用乳突根治术19例，外耳道局部切除2例，颞骨次全切除1例；放射治疗剂量3 500～10 000 cGy，平均6 560 cGy。
Methods: The healthy human PBMC was cultured with hCG at 37 ℃, 5%CO2 for 2 hours. The mRNA of harvested cells was isolated. The MIF mRNA was detected by real-time RT-PCR. Results: In a certain range of doses, the mRNA expression of MIF significantly increased following the increase of hCG in a dose depandent manner, and it reached to a peak 1-2 hours after culture, then returned to the minimum level after 8 hours.
分离正常人PBMC，体外加入不同浓度的hCG，在37℃5%CO2条件下培养一定时间收获细胞或加入一定浓度的hCG，同样条件下培养，在不同时间收获细胞，用荧光定量PCR方法检测MIF mRNA转录水平。