The variations of CKC may be the main reason for the chromosomalnondisjunction during meiosis that is attributed to the adverse pregnancy.
CKC变异频率增高可能是导致不良孕产非整倍体形成的主要原因之一。
In aneuploidy detection test TNT did not induce X and Y chromosomalnondisjunction, but induced the loss of X or Y chromosome with a good dose-response relationship.
STR-PCR technique was used to amplify 4 loci on chromosome 21, 3 loci on chromosome 18 and 3 loci on chromosome 13 to diagnose those chromosomal trisomies as well as the parental origins of the extra chromosomes and the stages of nondisjunction.