The mutagenicity of Ethrel was studied by Ames test, sperm deformity test and marrow micronucleus test in mice.
用Ames 试验、小鼠骨髓细胞微核试验及小鼠精子畸形试验对乙烯利进行了致突变作用研究。
This paper reports the antimutagenesis effect of three different preparations of five kinds of Chongqing green tea on four direct and indirect mutagens with Ames test.
本文采用沙门氏菌回复突变试验研究了五种重庆绿茶的三种样品制备形式对四种直接和间接致突变剂体外致突变性的抑制作用。
Ccording to the Ames test specification, TA97, TA98, TA100 and TA102 strains were used and the ammounts of 3 kinds of dust and their mixture with benzopyrene were 5000, 500, 50 and 5 μg/plate, respectively. The number of colony was counted after culturing for 48 h at 37 ℃. SCE test was performed with peripheral blood lymphocytes of healthy men. The ammounts of 3 kinds of dust and their mixture with benzopyrene were 500, 50 and 5 μg/plate, respectively. The chromosome specimen slide was made after culture 72 h at 37 ℃ and the frequency of SCE was counted. There were triplicate plates in each group and negative and positive controls were set up in Ames and SCE tests.
mes试验采用TA97、TA98、TA100和TA102菌株，将3种煤尘颗粒及其与苯并芘混合物各分为5000、500、50和5 μg/皿4个剂量组，并分为加与不加S9两部分，细菌37 ℃培养48 h后计算回变菌落数；SCE试验采用健康成人外周血淋巴细胞，煤尘颗粒及其与苯并芘混合物样品分为500、50和5 μg/皿3个剂量组，标本37 ℃培养72 h后制成染色体并计数染色单体交换频率。2个试验均设阴性和阳性对照组，各剂量组均设3个平行样。
Keywords: sulfur mustard; Ames test; mutation
硫芥；Ames试验；突变
In this study, we determined that the antimutagenic properties of various tea extracts including green, oolong, pu-erh tea, and black tea and six polyphenols include rutin, quercetin, apigenin, gallic acid, umbelliferone, and tannic acid were examined by Ames test which is a widely applied short-term bacterial assay for detecting DNA damage effect of mutagen.
在本篇研究中，我们探讨利用Ames test的方法筛检不同品种茶类包括绿茶、乌龙茶、普洱茶、红茶和数种常见的多酚类化合物包括单宁酸tannic acid、gallic acid、rutin、umbelliferone、apigenin、quercetin对於抑制PhIP（2-amino-1-methyl-6-phenylimidazo(4，5-b)pyridine）和 2-AAF（2-Acetylaminofluorene）两种致突变剂的抗突变作用。
Methods: The Ames test, MTT assay and alkaline phosphatase activity test were carried out to evaluate the influence on the mutagenesis rates of murine typhoid salmonella, on the PDLF and rabbit osteoblasts by different density nHAC leaching liquid.
采用Ames致突变试验、MTT法及碱性磷酸酶检测法，测定不同浓度胶原基纳米骨的浸提液对鼠伤寒沙门菌的致突变比值的影响和对人牙周膜成纤维样细胞及兔成骨细胞的影响。
objective to study genetoxic effect of reclaimed water in tianjin. methods reverse phase c-18 solid-phase extraction (rp-c18spe) was used for the extraction of target compounds from water samples. cell cytokinesis block micromuclei test and ames test were used to detect genetoxic. results ames test showed that both untreated reclaimed water and treated reclaimed water could induce mutation of ta98 and ta100 strains. but cell cytokinesis block micronuclei test was negative. conclusion ames test showed that after treatment, organic pollutant was not completely removed in recaimed water, which showed mutation effects.
目的 研究城市回用水的遗传毒性。方法利用固相萃取技术提取城市回用水中有机物，采用ames试验、体外胞质阻滞法微核试验检测其遗传毒性。结果在无代谢活化系统的条件下2次水样萃取物ta98和ta100在相当于原水2000ml/皿剂量时均出现不同程度的抑菌现象，2次水样各剂量组回变菌落数呈剂量-反应关系，其中1000ml/皿均超过自然回变菌落数的2倍，表明水样对ta98和ta100突变菌株有诱变作用。但在体外胞质阻滞微核试验中，城市回用水并未显示出明显的遗传毒性。
It could seem from running: this period can advance for the rate for the eligibility of CODMn, Ammonia, manganese, it also could be better about color, E254, Taster and Ames test.
运行表明，组合工艺可以提高高锰酸钾指数﹑氨氮﹑锰的合格率，改善色度﹑紫外吸光度﹑嗅味和致突变性等多项水质指标。
Based on toxicological test methods of pesticides for registration, animal experiments of acute oral toxicity, accumulative toxicity, subchronic toxicity, dermal sensitization study, bone marrow cell micronucleus test, teticale cell chromosome aberration analysis and Ames test were carried out.
本研究按照农药登记毒理学试验方法(GB15670-1995)，对毒菌锡原药进行了大鼠急性经口毒性试验，蓄积性毒性试验，亚慢性(90天)混饲经口毒性试验，小鼠骨髓细胞微核率，小鼠睾丸初级精母细胞染色体畸变率试验，以及Ames试验和皮肤致敏试验。
Methods Mice bone marrow cell micronucleus test, the mice sperm abormality test, Ames test and the teratogenicity test were carried out.
采用小鼠精子畸形试验、小鼠胸骨髓微核试验、Ames试验及大鼠传统致畸试验进行检测。
Methods: Acute toxicity test, 30 days feeding test and teratogenicity test were carried out to judge the general toxicity and embryotoxicity of perilla seed oil.
通过小鼠急性毒性试验，大鼠30天喂养试验和传统致畸试验，研究紫苏油的急性，亚急性毒性和胚胎毒性；Ames试验、小鼠骨髓细胞微核试验和小鼠睾丸染色体畸变试验，研究紫苏油的遗传毒性。
Methods: Acute toxicity test, 30 days feeding test and teratogenicity test were carried out to judge the general toxicity and embryotoxicity of TBF. Ames test, micronucle test of bone marrow cell as well as chromosome aberration test in mice were used to detect the genetic toxicity.
通过小鼠急性毒性试验，大鼠30天喂养试验和传统致畸试验，研究苦荞黄酮的急性、亚急性毒性和胚胎毒性；Ames试验、小鼠骨髓细胞微核试验和小鼠睾丸染色体畸变试验，研究苦荞黄酮的遗传毒性。
Objective To detect mutation and teratogenicity of isomalt which is a new kind of sugar replacer. Methods Mice bone marrow cell micronucleus test, the mice sperm abormality test, Ames test and the teratogenicity test were carried out.
目的 确保异麦芽酮糖醇的食用安全，对其进行了致突变性和致畸性研究方法采用小鼠精子畸形试验、小鼠胸骨髓微核试验、Ames试验及鼠传统致畸试验进行检测。
MATERIAL AND METHODS: The water extract of Danshen tea was examined by the mice bone marrow cell micronucleus test, the mice sperm abormality test, Ames test and the teratogenicity study.
材料与方法：材料主要用丹参茶浸泡液、大、小鼠和Ames试验菌株TA97、TA98、TA100、TA102；方法主要有小鼠精子畸形试验、小鼠胸骨髓微核试验、Ames试验及大鼠传统致畸试验。
Purpose and Methods: By Ames, micronucleus test on mouse bone marrow polychromatic erythrocytes and fish peripheral blood erythrocyte the mutagenicity of concent rated substance with XAD - 2 big hole resin is studied in the out2factory water, tip water, cement chamber water, boiling water and source water.
目的与方法：本文采用Ames 试验、小鼠骨髓嗜多染红细胞微核试验、鱼外周血有核红细胞微核试验，对基本饮用水的水源水、出厂水、末稍水、水泥水箱水、开水经XAD - 2 大孔树脂吸附、丙酮洗脱的浓缩物进行致突变性研究。
MATERIALS AND METHODS: The Ames test, the mouse micronucleus test and the mouse sperm abnormality test were used to evaluate the genotoxicities of bezoar antidotal tablet.
材料与方法：采用 Ames试验、小鼠骨髓细胞微核试验和小鼠精子畸形试验对牛黄解毒片进行遗传毒性检测。
Ames test showed that maneb groups didn't cause double increase of revertants.
在Ames试验中，4株试验菌在0.11.0 mg皿／的试验剂量下均没有引起自发回变数2倍增加。
Epstein-Barr Virus, activation test, Ames test and SOS Chromotest were used to study the foods and pla...
经用EB病毒-激活试验和检测致突变物的A〓和SOS试验对鼻咽癌高发区的食物和植物进行了研究。
The mutagenicity of TNT and its metabolites 4-hydroxylamino-2, 6-dinitrotoluene (4-HA), 4-amino- 2, 6-dinitrotoluene (4-A), 2-amino-4, 6-dinitrotoluene (2-A) and 2, 4-diamino-6-nitrotoluene (2, 4-DA) has been detected with Ames test.
应用Ames试验检测系统观察了三硝基甲苯及其还原代谢产物4-羟氨基-2，6-二硝基甲苯（4－HA），4-氨基-2，6-二硝基甲苯（4－A），2-氨基-4，6-二硝基甲苯（2－A）和2，4-二氨基-6-硝基甲苯（2，4－DA）的诱变活性。
Ames experiment was conducted by using PCB induced bandicoot liver homogenate as the out-of-body metabolism activation system; Cellula medullares micronucleus test was carried out by giving mice 0.07, 0.13, 0.33, 0.66 g/kg of medicine at intervals of 24 h; Teratospermia test was performed by giving mice 0.17, 0.33 and 0.66 g/kg. bw of medicine through intraperitoneal injection.
采用多氯联苯诱导的大鼠肝匀浆(S9)混合液作为体外代谢活化系统进行Ames试验；采用间隔24 h小鼠腹腔注射0.07，0.13，0.33，0.66 g/kg受试药品法进行骨髓细胞微核试验；采用小鼠腹腔注射0.17，0.33，0.66g/kg苷肽注射液进行精子畸形试验。