ResultsComparing with gonadectomy Shenyangxu model group, Wenyangyishen Capsules can improve upset excitability of male rat of gonadectomy penis Home News for Overseas Service Department, shorten erection incubation period; The rat increasing gonadectomy male sex attaches weight modulus of sexual organ; Can urge the hypophysis, adrenal gland weight modulus to increase by, weight adjusting the thymus gland, spleen; Elevate rat serum testosterone、Cortisol contents obviously; Be caused by messenger Cortisol the various Shenyangxu model small rat symptom gets laxation disappear even.
结果 与去势肾阳虚模型组比较，温阳益肾胶囊能提高去势雄性大鼠阴茎对外部刺激的兴奋性，缩短勃起潜伏期；增加去势雄性大鼠附性器官的重量系数；能促使垂体、肾上腺重量系数增加，调节胸腺、脾脏的重量；明显升高大鼠血清睾酮、皮质醇含量；使氢化可的松所致阳虚小鼠各项症状得到缓解甚至消失。结论温阳益肾胶囊具有益肾壮阳的功效。
Objective: To observe the effects of curcumin on the structure of adrenal gland, the level of serum ACTH and immune function in chronically stressed rats.
目的：探讨姜黄素对慢性不可预知应激模型大鼠的肾上腺结构、血清促肾上腺皮质激素浓度和免疫功能的影响及其意义。
RESULTS:Yanfuchun can increase the levels of serum E2 and plasma ACTH, increase the contents of NA and DA in hypothalamus, decrease the ratio of 5-HT/DA and 5-HT/NA, increase the index of adrenal glands in the middle-aged female rats.
结果：延妇春可使12～14月龄的雌性大鼠血清E2水平升高，血浆ACTH升高；使其下丘脑NA、DA含量升高，5-HT/DA、5-HT/NA比值降低，同时还可增加大鼠肾上腺重量。
Results: The above-mentioned indexes of the treatment groups were better significantly than of the model group. Compared in treatment groups, the changes of the number of EC and MC; and the serum INF-γconcentration had no significantly difference; The other indexes of the high dose group were better than of the small dose group, while had no difference in the prednisone group. The average weight of thymus, spleen, adrenal gland comparison, of prednisone group were lighter than of the normal guinea-pigs group, the model group and the high dose group, while there were no difference among the 3 groups.
结果 各治疗组与模型组比较，均能延长豚鼠引喘潜伏期、降低BALF细胞总数和EC数、降低血EC和MC数、降低血清IL-4和TXB2水平、升高INF-γ和6-keto-PGF1(下标 1α)水平；各治疗组比较，除血EC和MC数、升高INF-γ水平三项指标无差异，其余指标合剂大剂量组作用优于小剂量组，呈剂量正相关，而合剂大剂量组与西药组作用相当；对照组、模型组、合剂大剂量组胸腺、脾及肾上腺重量比较无显著性差异，但西药组低于此三组，差异有显著性。
Methods: 80 guinea-pigs were divided randomly into 5 groups, the guinea-pigs in the 2, the 3, the 4 and the 5 group were made modle. Subsequently, each group grinea-pigs were fed partly distilled water, Preinisone and FM with different doses. After 14 days, recorded the time of appearing gasp after the last touch stimulus; toke count of the cell routine of BALF and EC, MC in blood; mensurated the Serum IL-4, INF-γ, TXB2, 6-kern-PGF1 concentration; weighed out the thymus, spleen, adrenal gland.
将80只豚鼠随机分为五组，其中2~5组豚鼠造模，然后每日上午各组分别给予蒸馏水、不同剂量防喘合剂、强的松灌胃，14d后观察引喘潜伏期、肺泡灌洗液细胞组分、血清IL-4、INF-γ、TXB2、6-keto-PGF(下标 1α)水平、血嗜酸性粒细胞和肥大细胞计数及胸腺、脾、肾上腺重量。
Volumes of toe, IL-1βand TNF-αin serum, spleen T lymphocyte proliferation response, thymus index and adrenal gland index were detected.
结果：与致炎模型组相比，赶山鞭黄酮能减轻AA大鼠左、右后足炎症(P.01)；降低血清中细胞因子IL-1β、TNF-α的含量(P.01，P.05)。
Because of ovary and spermary not developing in babyhood, the estrogen in serum is mainly from adrenal, and the low level of estrogen persists until prepuberty.
雌激素是一类具有广泛生物活性的甾体激素，主要由卵巢分泌，睾丸及肾上腺也能分泌少量。
The quantitative analysis of β-END in tissues and serum showed that the con- tents of β-END in hypothalamus, pituitary, adrenal gland and serum were very close be- tween the control group and the normal group.
组织和血浆β-END定量分析显示，对照组的下丘脑、垂体、肾上腺和血浆的β-END相对含量同正常组接近，艾灸治疗未引起下丘脑β-END含量明显变化，但垂体和肾上腺β-END含量则显著下降，血浆β-END含量显著上升，表明垂体和肾上腺释放β-END入血。
Result: KYN could obviously increase the index of uterus and adrenal gland in OVX rats, and enhance the contents of E2, IL-2 and BGP. The level of FSH, LH, PRL in serum were decreased.
结果：坤怡宁能增加去卵巢大鼠子宫和肾上腺系数，提高其降低的E2，IL-2和BGP，显著降低去卵巢大鼠升高的FSH，LH和PRL。
Main results of animal experiments: For model rats of chronic immobilization stress, weigh-gaining slowed down and fodder intake was less; time staying in the central grid prolonged and times of grid-crossing were much fewer in open field test; times of wriggling were fewer in tail-suspending test; index of adrenal gland markedly increased and no visible change occurred in the index of thoracic gland; transformation function of spleen lymphocyte and phagocytosis of enterocoelia phagocyte were suppressed; content of serum IL-1〓 increased; contents of IL-2, IL-6 and IFN-γ decreased and the change of their contents was more visible over time; counts of positive cell and points of optical density of BDNF and NT〓 in cortex and hippocampus were lower and above-noted result of TrkB was markedly higher; expression of mRNA of enkaphalin and prodynorphin in hippocampus of rats increased; many other genes in hippocampus changed such as NO7, 41, 11, 18 with gene expression reinforcement (Rattus norvegicus similar to RIKEN cDNA 6720467C03 gene), 28 [Mus musculus similar to ATP-binding cassette, sub-family A (ABC1), member 3 (LOC328776)], 23 (Rattus norvegicus complete mitochondrial genome) and 8 with weak gene expression; behavior of model rats was able to be changed by all three recipes and stationary time in tail-suspending test shortened only in Xiaoyaosan group; all three recipes enhanced the transformation function of lymphocyte and phagocytosis of phagocyte induced by ConA and increased the content of serum IL-1〓 and Sijunzitang alone had no effect on the content of serum IL-2, IL-6 and IFN-γ; all three recipes were able to prevent counts of positive cell as well as points of optical density of BDNF as well as NT〓 from decrease and trkB from increase in the cortex and hippocampus to different extent; all three recipes were able to decrease the gene expression of pro-dynorphin mRNA and Xiaoyaosan as well as Sijunzitang were able to decrease the gene expression of enkaphalin mRNA and action of Xiaoyaosan was better on these two indices than Jinkuishenqiwan; Xiaoyaosan could decrease the gene expression of №: 7, 11, 26, 42 and reinforce expression of №: 8, 28, activated the expression of №: 12 in hippocampus. Main conclusions were as follows.
三个复方都能够改善大鼠的行为学，都能缩短中央格停留时间，增加穿格次数和挣扎次数，但是只有逍遥散能够缩短悬尾实验中大鼠的静止时间；三个复方都对胸腺指数没有明显的影响；三个复方都增强了ConA诱导的淋巴细胞转化功能和巨噬细胞吞噬功能，能降低血清IL-1〓的含量，逍遥散和金匮肾气丸能升高血清IL-2、IL-6和IFN-γ的含量；三个复方均能升高皮层BDNF的积分光密度和海马中BDNF的阳性细胞数；逍遥散能降低海马和皮层中的TrkB阳性细胞数和海马TrkB的积分光密度；四君子汤和金匮肾气丸能降低皮层TrkB的积分光密度；金匮肾气丸能降低皮层TrkB的阳性细胞数；逍遥散升高皮层和海马中BDNF的作用比四君子汤和金匮肾气丸强；三个复方均能升高皮层和海马NT〓的积分光密度和海马中NT〓的阳性细胞数，逍遥散能升高皮层NT〓的阳性细胞数；三个复方均能降低海马内前强啡肽mRNA的表达，逍遥散和四君子汤能降低Enk mRNA的表达，逍遥散对这两个指标的改善作用明显优于金匮肾气丸组；逍遥散能够降低海马内7号、11号、26号、41号基因的表达；增强8号、28号基因的表达，可以使12号基因表达。
Further workup revealed a high serum aldosterone and a low serum renin, findings consistent with an aldosterone secreting adrenal adenoma (Conn's syndrome).
进一步检测发现醛固酮升高和肾素降低，结果与醛固酮分泌性肾上腺腺瘤（Conn综合症）一致。
COMPARATIVE PHARMACOLOGY OF CHINESE RED GINSENG AND KOREAN RED GINSENG & I. Effects on adrenal as well as serum corticosterone and its mechanism
中国红参与朝鲜红参药理作用的比较&1.对血清及肾上腺皮质酮的影响与作用机理
Objective: To observe the dynamic changes of some pituitary, adrenal, thyroid and sex hormones in serum of rats irradiated by 99 W · cm 2 high power pulse microwave (HPPMW), so as to explore its influence on endocrine system.
目的：观察高功率脉冲微波（HPPMW）辐照后大鼠血清中垂体、甲状腺、肾上腺及性腺部分激素的动态变化，以探讨HPPMW对内分泌系统的影响。
Biological Effects of Abdominal Irradiation on Adrenal Function in Mice Reflected as Changes of Serum Cortisol Concentration
小鼠腹部照射后肾上腺皮质醇分泌含量变化及生物学效应
Effect of sport training on adrenal cortical hormones and gonadal axis hormones in serum of students
运动训练对大学生血清甾体激素的影响
Methods: [Ca 2 +] I of hypothalamus pituitary adrenal axis and lymphocyte of blood in rats were tested with flow cytometry by using [Ca 2 +] I fluorescent probe Flou 3/AM, as well as serum calcium.
方法：用流式细胞仪及钙荧光探针Flou3AM对肾阳虚大鼠下丘脑垂体肾上腺轴、血淋巴细胞胞内Ca2+（[Ca2+]i）和血清钙进行测定。
The results showed that in the rats in the model group, levels of serum CPK and LDH, plasmatic ET and cerebral NPY were increased, and the excitability of sympathetic adrenal system was reinforced;
模型组血清中CPK、LDH活性和血浆ET及脑组织NPY含量增高，交感-肾上腺系统兴奋增强。
The levels of plasma ACTH and serum cortisol were observed in 13 patients with primary adrenal failure, 31 patients with secondary adrenal failure, and 42 healthy persons.
本文报告原发肾上腺皮质功能减退（PAF）患者13例、继发肾上腺皮质功能减退（SAF）患者31例及正常人42名血浆ACTH及血清皮质醇测定的结果。
[Conclusion] Serum testosterone, combined with clinical significance and blood chemistry are contributed to early diagnosis of congenital adrenal hyperplasia in newborns with skin hyperpigmentation.
【结论】对于皮肤色素加深的新生儿，血清睾酮的测定有助于CAH的早期诊断，但应结合临床和血生化检查。对血清睾酮同样增高而不伴电？
Conclusion: The cortisone levels in serum in rats with suprarenalectomy could reach almost normal after micro-encapsulated adrenal cortex cells were transplanted.
结论：接受微囊化肾上腺皮质细胞移植后肾上腺功能低下大鼠的血清皮质醇水平可接近正常值。