In this observational study, 65 children were treated with SLIT with a build-up phase of 11 days, culminating in a peak dose of 300 IR, and followed by a maintenance phase of 300 IR three times weekly. There were 51 boys and 14 girls; age range was 38 to 80 months (median age, 60 months). Allergens used were house dust mites in 42 patients, grass pollen in 11, olive pollen in five, Parietaria pollen in four, and cypress pollen in three patients. Adverse reactions and changes in the treatment schedule were compared in children aged 38 to 60 months vs those aged 61 to 80 months.
在这项观察性试验中，65位接受SLIT的儿童在11天的适应期后，将剂量逐渐调整到最高300 IR，接著以每周3次，每次300 IR的剂量持续接受治疗；试验中包括51位男童与14位女孩，年龄介于38至80个月（平均年龄为60个月）；其中有42位病患以尘蹒、11位以花粉、5位以橄榄花粉、4位以墙草、3位以丝柏作为过敏原；年龄介于38至60个月的儿童，与61至80个月的儿童分成两组比较不良反应发生机率与治疗疗程的改变。
Atopy was defined as a positive skin-prick test to mites, cat, Alternaria, Cladosporium, grass, birch, Parietaria, olive, or ragweed.
特应性定义为对螨类、链格孢属、分子孢子菌属、草、桦木、墙草属、橄榄或豚草属皮肤划痕实验阳性。
Any of various monoecious plants of the genus Parietaria, having long, narrow leaves with hairy tufts at the base and apetalous flowers.
墙草属植物任一种雌雄同株的荨麻属植物，长有茎部带有毛簇的细长的叶子和无花瓣的花