Objective To study the effect of Mycobacterium smegmatis vaccine on the level of nitric oxide produced by peritoneal macrophages in immunized mice.
目的 探讨耻垢分枝杆菌疫苗对小鼠腹腔巨噬细胞产生一氧化氮的影响。
ABSTRACT:Objective To study the effect of Mycobacterium smegmatis vaccine on the level of nitric oxide produced by peritoneal macrophages in immunized mice.
目的 探讨耻垢分枝杆菌疫苗对小鼠腹腔巨噬细胞产生一氧化氮的影响。
Mycobacterium smegmatis vaccine can promote the peritoneal macrophages to produce NO in mice.
耻垢分枝杆菌疫苗可促进小鼠巨噬细胞产生一氧化氮。
Objective To construct and identify living recombinant Mycobacterium smegmatis MC2155 vaccine containing P30-ROP2 compound gene of Toxoplasma gondii.
目的构建和鉴定弓形虫P30-ROP2复合基因重组耻垢分枝杆菌M。
The E. coli-Mycobacterium shuttle plasmid for UreI gene was successfully constructed and expressed in Mycobacterium smegmatis.
结论已成功构建了幽门螺杆菌尿素通道蛋白UreI基因大肠杆菌－分枝杆菌穿梭表达质粒，并在耻垢分枝杆菌中获得表达。
Results: The distribution of GFP and recombinant Mycobacterium smegmatis in lung and spleen was detected. The expression of GLS, the increased of IL-12 in serum and the specific SIgA in BALF were found.
结果：在BALB/c小鼠肺、脾组织中均检测到绿色荧光蛋白和耻垢分枝杆菌的分布，以及GLS的表达，并有血清IL-12水平升高和粘膜特异性SIgA的产生。
It is feasible to targetedly deliver eukaryotic expression plasmids into macrophages by using Mycobacterium smegmatis as an attenuated biological vector.
利用耻垢分枝杆菌作为减毒生物体载体向巨噬细胞中靶向递送真核表达质粒是可能的。
Conclusion Mycobacterium smegmatis vaccine can promote the peritoneal macrophages to produce NO in mice.
结论耻垢分枝杆菌疫苗可促进小鼠巨噬细胞产生一氧化氮。
Study of Recombinant Mycobacterium Smegmatis Live Vector Vaccine Expressing the 26KD Outer Membrane Protein of Helicobacter Pylori
幽门螺杆菌外膜蛋白Omp26重组耻垢分枝杆菌活载体疫苗的研究
ABSTRACT: Objective To study the effect of Mycobacterium smegmatis vaccine on the level of nitric oxide (NO) produced by peritoneal macrophages in immunized mice.
摘要：目的探讨耻垢分枝杆菌疫苗对小鼠腹腔巨噬细胞产生一氧化氮的影响。
Effect of Mycobacterium Smegmatis Vaccine on the Level of Nitric Oxide Produced by Peritoneal Macrophages in Mice
耻垢分枝杆菌疫苗对小鼠巨噬细胞产生一氧化氮的影响
Objective To construct recombinant Mycobacterium smegmatis expressing ESAT-6 of the human pathogen Mycobacterium tuberculosis.
目的构建表达结核分枝杆菌ESAT-6基因的重组耻垢分枝杆菌并对其免疫功能进行研究。
The Dnd phenotype was also found in DNA of Mycobacterium smegmatis mc 2155 by PFGE.
在PFGE中发现耻垢分枝杆菌mc~2155也具有Dnd表型。
The effect of immunization by recombinant Mycobacterium smegmatis encoding GLS and IL-12 in mice
GLS和IL-12偶联重组耻垢分枝杆菌免疫效果的观察
Experimental Research on a Recombinant Mycobacterium Smegmatis Therapeutic Vaccine Delivering GLS/IL-12 to Specific Target
靶向递送GLS/IL-12真核共表达质粒的重组耻垢分枝杆菌治疗性活疫苗的实验研究
The specific anti-bacterium SIgA is generated. GLS and IL-12 are expressed in BALB/C mice after intranasal immunization with recombinant Mycobacterium smegmatis carrying the plasmid encoding GLS and IL-12.The results lay the foundation for new vaccine study.
携带GLS和IL-12的重组耻垢分枝杆菌经鼻粘膜免疫小鼠后，可引起呼吸道粘膜特异性抗菌免疫，以及GLS和IL-12的体内表达，为新型疫苗的研究奠定了基础。
This article clarifies the advance in the research of construction and its immune responses of4 types of recombinant Mycobacterium smegmatis vaccines of MTB.
文章介绍了4种结核分枝杆菌重组耻垢分枝杆菌疫苗的构建及其免疫机制等方面的研究进展。
Construction of recombinant Mycobacterium smegmatis expressing ESAT-6 and its effects on macrophages
表达结核杆菌ESAT-6基因重组耻垢分枝杆菌的构建及其功能研究
Establishment of recombinant Mycobacterium smegmatis secreting IL-2
表达人白细胞介素-2重组耻垢分枝杆菌疫苗株的建立
Immune Response Elicited by Recombinant Mycobacterium smegmatis Expressed HBV Fused Gene in Mice in vivo
小鼠对表达HBV截短肽的耻垢分枝菌的免疫应答