Strains of fungi were detected, among them, 62 (71.3%) were Monilia, 17 (19.5%) mold fungus, and 7 (8.0%) budding fungus. The most common Monilia were Monilia albicans, slick Monilia and Oidium tropicale.
感染菌谱中真菌87株，其中念珠菌62株(71.3%)，毛霉菌17株(19.5%)，酵母菌7株(8.0%)，念珠菌中常见的菌种依次为白色念珠菌、光滑念珠菌和热带念珠菌。
Results: Of the 70 cases, Monilia albicans accounted for 61.43%, slick Monilia 21.43%, Candida tropicalis 11.43 and Candida Krusei 5.71%.
结果：念珠菌感染70例中，白色念珠菌占61.43%，光滑念珠菌占21.43%，热带念株菌占11.43%，克柔念株菌占5.71%。
Results totally 287 strains were isolated from the 256 positive samples, and the gram-negative bacilli were 225(78.4%, ), the gram-positive coccus were 41(14.3%), snd the monilia were 21(7.3%).the distributions of clinical bacteria were respiratory tract(63.4%), urinaryract(7.0%), secretion(includingwound.3%), blood(5.9%), stool(5.2%), pucture fluid(4.9%), and other sites(7.3%). of all isolating bacterium, from the first to the fifth were ps. aeruginosa(19.5%), k. pneumoniae(16.7%), e. coli(14.3%), a. baumannii(11.8%) and psemal (10.1%).resistant rates of methecillin-resistant s. aureus, methecillin-resistant coagulase-negative staphylococci and vancomycin-resistantwere 88.2%、70.0% and 11.1% respectively; the incidence of e. coli and k. penumoniae produce extended speutrum beta-lactamase were 68.6%和65.2%, 44.6% of ps. aeruginosa isolates were resistant to imipenem; the highest examining rate of 21 kinds of monilia was candida albicans (66.7％), resistant rate of candida albicans to fluconazole and amphotricin b was 51.3％ and 1.3%.
结果 在254份检出细菌阳性标本中共培养出287株细菌，其中革兰阴性杆菌225株（78.4％），革兰阳性球菌41株（14.3%），念珠菌21株（7.3%），检出菌来自呼吸道标本占63.4%，其他标本各占5%左右；细菌检出占构成比前三位的依次为铜绿假单胞菌19.5%、肺炎克雷伯菌16.7%、大肠埃希菌14.3%；耐甲氧西林金黄色葡萄球菌、耐甲氧西林凝固酶阴性葡萄球菌和耐万古霉素的肠球菌的发生率分别为88.2%、70.0%和11.1%；大肠埃希菌和肺炎克雷伯菌的超广谱β-内酰胺酶的检出率分别为68.6%和65.2%，铜绿假单胞菌对亚胺培南的耐药率为40.2%；白色念珠菌对氟康唑的耐药率为81.3％，对两性霉素的耐药率为3.2%。
Objective To analyze the results of drug sensitive test of384strains of Monilia albicans infec-tion, so as to provide assistance to the reasonable use of antibiotics clinically.
Cs#K R8Rcfn：F 目的分析384株白色念珠菌的药物敏感性，以指导临床合理用药治疗真菌感染。
The following examining methods were carried out:(1)Phagocytosis of Monilia albicans by the peritoneal macrophages by means of fluorescence microscopy after acridine orange staining.(2)Measurement of non-specific esterase in Mφ after being stained with α-nephthy acetate by image analysis.
激光照射结束后取小鼠腹腔巨噬细胞，分别做如下实验：(1)用荧光显微镜观察腹腔巨噬细胞对白色念珠菌的吞噬功能；(2)用α-荼酚醋酸酯法显示腹腔巨噬细胞内非特异性酯酶，并用图像分析系统对NSE作定量分析；(3)用透射电镜观察腹腔巨噬细胞超微结构的变化。
Methods The double-diluted drugs were cultured with 11 species of bacteria, 105 test plants such as staphylococcus, streptococcus, Gbacillus, catarrh diplococcus, monilia albicans etc. in vitro, then MIC50, MBC50 were measured.
采用二倍稀释法，将不同浓度药物与葡萄球菌、链球菌、G杆菌、卡他双球菌、白色念珠菌等11类菌种，共105个试验菌株体外培养，测定 MIC50，MBC50。
Results Two cases were pulmonary tuberculosis combined aspergillus infection; one case was NK cell precursor acute leukemia and aspergillus infection; one case pernicious leucopenia and monilia infection; one case sjogren syndrome or diabetes both combined with candida albicans infection. CT basic manifestations included effusion or nodules or cavities or tumour.
结果 2例肺结核并曲霉菌感染，1例恶性白细胞细胞减少并念珠菌感染，1例急性NK细胞白血病并曲霉菌感染，干燥综合征及糖尿病各1例并白色念珠菌感染，CT基本表现为渗出、结节、空洞、肿块病灶。
The isolated fungi during 2004~2005 accounted for 15.13%~18.78% respectively, with monilia, in particular, blastomyces albicans showing the highest proportion, accounting for about 63% in respective year.
2004年～2005年我院分离的真菌菌株数分别占全年病原菌总分离数的15.13%～18.78%，真菌主要为念珠菌，以白色念珠菌为多，占真菌总数的63%左右。
Results 62 strains of Monilia, 74.2% of which was Candida albicans and 22.6% was Miliaria albicans, were identified.
结果检出念珠菌62株，以白色念珠菌为主，占74.2%，其次为热带念珠菌占22.6%。
Results: Candida albicans occupied 57.1% in 665 fungi, Candida tropicalis, slick Monilia and Candida kruse occupied 24.8%? 16.2% and 1.4% respectively.
结果：665株真菌中白色念珠菌占57.1%，其次是热带念珠菌、光滑念珠菌、克柔念珠菌，分别为24.8%、16.2%、1.4%。
Analysis of antifungal resistance of 384 strains of Monilia albicans
384株白色念珠菌的药物敏感性分析
Objective To analyze the results of drug sensitive test of 384 strains of Monilia albicans infection, so as to provide assistance to the reasonable use of antibiotics clinically.
目的分析384株白色念珠菌的药物敏感性，以指导临床合理用药治疗真菌感染。
Among pregnant women, monilia albicans carrier rate in the first trimester is 0.8%, in the middle trimester 2.5%, and in the last trimester 6.8%.
妊娠妇女中，早期妊娠白念珠菌带菌率为0.8%，中期妊娠为2.5%，晚期妊娠为6.8%。
ResultsThe MIC50 and MBC50 to staphylococcus were 2.75 mg/ml and 5.5 mg/ml; the MIC50 and MBC50 to pneumonia streptococcus were 5.5 mg/ml and 22mg/ml; the MIC50 and MBC50 to flu, proteus, pneumonia bacillus were 11 mg/ml, 22 mg/ml and 44 mg/ml; the MIC50 and MBC50 to streptococcus, aeruginous bacillus, catarrh diplococcus, monilia albicans were 22 mg/ml and 44 mg/ml.
结果银黄注射液对金葡菌、表葡菌的 MIC50为2.75 mg/ml，MBC50为5.5 mg/ml；对肺炎链球菌 MIC50为5.5 mg/ml，MBC50为22 mg/ml；对流感、变形、肺炎杆菌的 MIC50为11 mg/ml，MBC50为22 mg/ml及44 mg/ml；对链球菌、绿脓杆菌、卡他双球菌、白色念珠菌的 MIC50为22 mg/ml，MBC50为44 mg/ml。
Results: Candida albicans occupied 57.1 % in 665 fungi, Candida tropicalis, slick Monilia and Candida kruse occupied 24.8 %? 16.2 % and 1.4 % respectively.
结果：665株真菌中白色念珠菌占57.1%，其次是热带念珠菌、光滑念珠菌、克柔念珠菌，分别为24.8%、16.2%、1.4%。
Results Twelve of 34 cases of candidemia were C. albicans, and 22 of 34 cases were non-C. albicans, which were 64.71% in candida monilia.
结果34例念珠菌血症患者中白色念珠菌12例，非白色念珠菌22例，非白色念珠菌感染者占念珠菌属感染者的64.71%。