The mechanism of Hofmann rearrangement reaction and the effects of alkyl structure and nucleophilic reagent in medium on the reaction are discussed.
讨论了Hofmann 重排反应的机理以及烃基的结构、介质中的亲核试剂对反应的影响，并介绍了此重排在有机合成中的应用。
Target compound pazufloxacin was synthesized through the Hofmann rearrangement reaction.
目的：优化帕珠沙星Hofmann重排反应的合成工艺。
Starch as a raw material is grafted on a reaction product which is made by Hofmann rearrangement of polyacrylamide.
以淀粉为原料使之与聚丙烯酰胺经霍夫曼重排反应产物进行接技反应而制得。
The mechanism of Hofmann rearrangement reaction and the effects of alkyl structure and nucleophilic reagent in medium on the reaction are discussed. Moreover, the application of Hofmann rearrangement reaction in organic synthesis is introduced.
讨论了Hofmann重排反应的机理以及烃基的结构、介质中的亲核试剂对反应的影响，并介绍了此重排在有机合成中的应用。
Medicine intermediate N-ethylethylenediamine (NEED) was synthesized from acrylamide and ethylamine by addition reaction and Hofmann rearrangement.
以丙烯酰胺为起始原料，经乙胺加成后，再经Hofmann重排两步反应后合成了药物中间体N-乙基乙二胺（NEED）。
A study on Hofmann rearrangement in two-phase system
两相体系中的Hofmann重排反应
Improved Hofmann rearrangement in baclofen synthesis
巴氯芬合成中Hofmann重排反应的改进