To clear the relationship between HN structure and function of paramyxovirus Tianjin strain, rHN1, rHN2 and rHN3 overlapping the ectodomain of HN protein were expressed. Their antigenicity and hemaglutination activity, as well as cross reactivity to standard antisera against influenza virus type A, type B were analyzed.
为了明确副粘病毒Tianjin株HN的结构与功能的关系,本研究表达了HN膜外区的三个片段HN1、HN2和HN3,对其抗原性、红细胞凝集活性和与甲、乙型流感病毒的交叉反应性进行了初步分析。