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[英文释义] Human histocompatibility (HLA) surface antigen encoded by the B locus on chromosome 6. It is in linkage disequilibrium with HLA-A1 and HLA-DR3. This explains the fact that though HLA-B8 was originally associated with several diseases,including celiac disease,dermatitis herpetiformis,and myasthenia gravis,their association with HLA-DR3 is now considered more significant.