Background Duchenne Muscular Dystrophy is an X-linked recessive lethal inherited disease, which involves skeletal and cardi...
Duchenne型肌营养不良症(Duchenne muscular dystrophy，DMD)是一种以骨骼肌进行性变性、坏死为主要表现的致死性X-连锁隐性遗传病。
February 21, 2007PTC Therapeutics of South Plainfield, N. J., will test a higher dose of its experimental compound PTC124 in approximately 12 boys with Duchenne muscular dystrophy caused by a premature stop codon mutation.
位在纽泽西州-南普兰费得的 PTC Therapeutics 公司将使用更高剂量的 PTC124 为大约12位裘馨型肌萎缩症病童进行治疗基因过早停止编码突变的试验。
Secondly, establish a reliable and sensitive technique of single cell 3-plex nested PCR for dystrophin and SRY gene, and evaluate the possibility of using this technique for preimplantation genetic diagnosis of deleted Duchenne muscular dystrophy with family history.
这5个家系中，共收集到41名成员的血标本，其中女性20名，经系谱分析已确定为dystrophin基因肯定携带者的有7名，待检者13名。
Like a tall building, this disease can cast a long shadow, but the Tessmer's prove there are cracks in Duchenne's foundation.
如高建筑下的影子，这种疾病投下了长长的阴影，但这三个男孩的证明，这建筑是有裂缝的存在。
Objectives To explore the clinical characteristics of the children with Duchenne muscular dystrophy and the diagnostic value of creatase, electromyogram and muscle biopsy.
目的探讨Duchenne型进行性肌营养不良的临床特点及肌酶、肌电图、肌肉活检的诊断价值。
This was successful in a mouse model of Duchenne muscular dystrophy.
这一新的递送抗肌萎缩蛋白基因的方法在对杜氏进行性肌营养不良实验鼠的实验中取得了成功。
The first signs of the Duchenne type of dystrophy usually appear before the age of three.
最初迹象的裘馨型的营养不良症通常出现之前，3岁。
Perhaps these three boys are nature's signal that a cure for Duchenne dystrophy can be found.
也许这三个男孩都是大自然的信号，一种治疗杜氏肌营养不良的信号。
Objective:To explore the application of freeze-etching electrom microscopy in the study of Duchenne muscular dystrophy.
目的：探讨电镜冷冻蚀刻技术在Duchenne型肌营养不良症研究中的应用。
Methods The clinical and laboratory data was analyzed in 40 children with confirmed diagnosis of Duchenne muscular dystrophy by dystrophin detection.
方法对40例经dystrophin蛋白检测确诊的DMD患儿的临床特征及实验室检查资料进行分析。
The severity of Duchenne and Becker muscular dystrophy is determined by the type of mutation.
而杜氏进行性肌营养不良和贝克型进行性肌营养不良的区别在于他们缺失突变的类型不同。
Duchenne smile, which is characterized by''crow`s feet wrinkles around the eyes and a
总体意思是依赖于后者，但是我们这里原文的感觉是前面的动词可以用来解释后面的，这个两者之间的关系在分量上好像有颠倒。
Five centers will support trials and studies in ALS (amyotrophic lateral sclerosis, or Lou Gehrig`s disease) and five will focus on Duchenne muscular dystrophy.
美国神经肌肉疾病协会即将建立的临床治疗网络包括十个美国神经肌肉疾病协会下属的临床医学研究中心，其中五个中心主要研究肌萎缩侧索硬化 ALS (amyotrophic lateral sclerosis，or Lou Gehrig`s disease)的临床治疗研究，五个针对杜氏进行性肌营养不良的临床研究中心。美国神经肌肉疾病协会每年对这十个研究中心提供100万美元的资助。这些资助的目的包括1。加快开发和试验新的治疗方法
Duchenne/Becker muscular dystrophy is an X-linked lethal recessive disease caused by mutation in the DMD gene.
假肥大性肌营养不良(Duchenne/Becker muscular dystrophy，DMD/BMD)是一种由于 DMD 基因突变导致的X连锁隐性致死性遗传病。
Objective:WT5BZUsing dinucleotide repeat polymorphism in the dystrophin gene as markers, we intended to improve prenatal diagnosis for Duchenne muscular dystroph families and to evaluate its feasibility.
目的：应用二核苷酸重复多态Duchenne型肌营养不良症基因诊断，探讨DMD产前基因诊断方案及其可行性。
Methods The latest fifteen-year literatures were extensively reviewed, concerning gene therapy for Duchenne＇s muscular dystrophy, Parkinson＇s disease, myelopathy, permanent facial paralysis, angiocardiopathy, injuries of bone, joint and muscle, hematopathy, and pituitary dwarf.
查阅国内外近15年来对Duchenne型肌营养不良、帕金森病、脊髓疾病、永久性面瘫、心血管系统疾病、骨、关节及肌肉损伤、血液系统疾病以及垂体性侏儒等的细胞治疗及基因治疗文献，并进行综合分析。
November 11, 2007 — The US Food and Drug Administration has granted orphan drug designation to AVI-4658 for the treatment of Duchenne muscular dystrophy, SQ109 for the treatment of tuberculosis, and ATIR for the topical treatment of graft-versus-host disease.
美国食品药品管理局近日批准以下三种孤儿药：AVI-4658用于杜兴肌营养不良病治疗、SQ109用于肺结核治疗、ATIR用于移植物抗宿主的局部治疗。
In the following decade, French neurologist Guillaume Duchenne gave a comprehensive account of 13 boys with the most common and severe form of the disease which now carries his name — Duchenne muscular dystrophy
在随后的十年中，法国神经学家纪尧姆杜兴时全面介绍了13个男孩最常见，最严重的疾病（现在带有他的名字-杜氏肌营养不良）。
The present invention is one medicine for treating Duchenne muscular dystrophy.
本发明涉及一种治疗杜兴氏肌营养不良疾病的药物。
Objective To study and contrast the expression of Dystrophin in skeletal muscle and in Arrector pili muscle of the patients with Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD).
目的研究、对比肌营养不良蛋白（dystrophin）在杜兴型肌营养不良（duchennemusculardystrophy，DMD）和贝克型肌营养不良（Beckermusculardystrophy，BMD）患者活检骨骼肌、皮肤立毛肌中的表达。