With representation of typical zeolites Y and ZSM-5, our energetic calculating results can well explain the results of Sreekumar et al about Thio-Claisen rearrangement with and without zeolite catalysts, which is that syn conformation is the main product without catalyst, while anti conformation is the only product with zeolite catalyst.
以Y和ZSM-5两种典型分子筛为例用能学计算结果能较好地解释Sreekumar等人有、无分子筛催化条件下Thio-Claisen重排手性反应结果，即：无催化剂时，反应产物以顺式为主，有分子筛介入时，只能生成反式产物。
From -1 was achieved using aza-Claisen rearrangement as a key step.
从-苯基甘氨醇1出发，整个合成路线经十步反应，总产率5.3％。
Based on the addition of vinyl magnesium bromide to the chiral non-racemic synthon 2 derived from-1, an enantioselective total synthesis of-3, the antipode of marine alkaloid halitulin 10 steps, overall yield: 5.3% from (R-1 was achieved using aza-Claisen rearrangement as a key step.
取得的主要结果如下：一、从-苯基甘氨醇1出发，通过已知的哌啶手性合成砌块2的加成反应，建立了经aza-Claisen重排反应进行海洋生物碱halitulin手性分子片断的对映体--isohaliclorensin 3不对称合成的路线。
Based on the addition of vinyl magnesium bromide to the chiral non-racemic synthon 6 derived from-1, an enantioselective total synthesis of-3, aconstituent of marine alkaloid hulitulin 10 steps, overall yield 5.9% from was achieved using aza-Claisen rearrangement as a key step.
以-苯基甘氨醇1为原料，整个合成路线共经十二步反应，总产率2.7％。二、从-苯基甘氨醇1出发，通过已知的哌啶手性合成砌块6的加成反应，建立了经aza-Claisen重排反应进行海洋生物碱halitulin的手性分子片断摘要---一-~----------C一沟一isohalidorensin3不对称合成的路线。
In part 1 of this thesis, we investigated Ireland-Claisen rearrangement of allyl esters of unsaturated acids systemically, and applied the rearranged products for derivation to some fragrant molecules; Four topics are addressed, which are: 1. We studied Ireland-Claisen rearrangement of allylic acrylates.
本论文第一部分工作对不饱和羧酸烯丙基酯类化合物的Ireland-Claisen重排进行了深入的研究，并将Ireland-Claisen重排产物的衍生化应用于潜香物质的合成，主要有以下四个方面：一、研究了丙烯酸烯丙酯类化合物的Ireland-Claisen重排反应。
2-Substituted-3, 4-dihydro-1(2H)-isoquinolinones were synthesized from methyl 3-hydroxy-ben- zoates via allyl etherification, Claisen rearrangement, oxidation, reductive amination and aminolysis for the first time.
以3-羟基-4-甲氧基苯甲酸甲酯等为原料，通过烯丙基醚化、Claisen重排、氧化、与伯胺反应、还原、分子内酯的胺解六步反应合成了一系列2-取代-3，4-二氢-1-异喹啉酮类化合物。
We studied DBU-mediated Ireland-Claisen rearrangement. Using DBU as the base for enolization of allylic esters of unsaturated acids 9-16, we found a novel DBU-mediated tandem Ireland-Claisen rearrangement /isomerization reactions and established a consecutive Ireland-Claisen rearrangement /Cope rearrangement.
利用DBU作为烯醇化碱，对含有活泼质子的烯酸烯丙酯类化合物9-16的Ireland-Claisen重排进行了系统的研究，创建了一条新颖的DBU-促进的Ireland-Claisen重排/异构化串联反应及Ireland-Claisen重排/Cope重排的串联反应路线。
Second, using DBU as the base for enolization of propargylic esters of unsaturated acids 18e-k, we developed a tandem Ireland-Claisen rearrangement /isomerization reactions. It has been shown that the reaction sequence affords triene molecules 42a-b and 43a-b in moderated to high yields. Interestingly, with allyl hexa-3, 5-dienoates 18i-j as the substrate, the rearranged products underwent further aromatization to give uniquely substituted benzyl acids 44a-b.
其次，以含有活泼质子的烯酸炔丙酯18e-k为底物，在DBU为烯醇化碱、TMSCl为硅试剂的条件下，底物18e-h发生了Ireland-Claisen重排/异构化串联反应，得到完全共轭的三烯类化合物42a-b及43a-b；而以己二烯酸炔丙基酯18i-j为底物时，重排/异构化后的产物进一步发生电环化等反应最终得到芳构化产物——取代苯甲酸类化合物44a-b。
Research Progress on the Synthesis of Benzofuran Derivatives from Claisen Rearrangement Products
以Claisen重排产物为原料合成苯并呋喃衍生物研究进展
Synthesis of diallyl bisphenol A by bulk Claisen rearrangement reaction Studies of Semipinacol Rearrangement
本体Claisen转位合成二烯丙基双酚ASemipinacol重排反应研究
Tandem Claisen rearrangement/Diels-Alder reaction in ionic liquid
离子液体中的Claisen重排/Diels-Alder加成串联反应研究
Studies on the Heck Reaction and Aza-Claisen Rearrangement Catalyzed by Ferrocenyl Palladic Compounds
二茂铁钯化合物催化Heck、Claisen重排反应研究
Quantum Chemical Study of Claisen Rearrangement
Claisen重排反应的量子化学研究
The conventional catalysts for Claisen rearrangement were Lewis acids, Bronsted acids, and solid catalysts.
报道的催化剂通常是路易斯酸、质子酸和固体催化剂等。
Application of bis (indeny) rare - earth hydride in Claisen rearrangement
二茚基稀土氢化物在Claisen重排反应中的应用
A nonadiabatic molecular dynamical study of the photo-claisen rearrangement
光CLAISEN重排反应的非绝热分子动力学研究
We studied Ireland-Claisen rearrangement of propargylic esters of unsaturated acids.
研究了不饱和羧酸炔丙酯类化合物的Ireland-Claisen重排反应。
Sigmatropic rearrangement studied in this thesis mainly includes Ireland-Claisen rearrangement and [2, 3]-Wittig rearrangement.
本论文研究的σ重排反应主要为Ireland-Claisen重排与[2，3]-Wittig重排。
First, when operating the DABCO-catalyzed Ireland-Claisen rearrangement of propargylic acrylates 18b-d, we added dienophiles 40a-f in the reaction system to capture the rearranged allenes products respectively. The Diels-Alder adducts 41a-i were obtained with complete regioselectivity. Thus a novel tandem Ireland-Claisen rearrangement /Diels-Alder reaction process with propargylic acrylates has been developed.
首先在进行DABCO-催化的丙烯酸炔丙酯类化合物18b-d的Ireland-Claisen重排反应的同时，于反应体系中分别加入亲二烯体40a-f捕获重排得到的连二烯中间体，一步反应获得了单一区域选择性的Diels-Alder环加成产物41a-i，从而创建了一条新颖的丙烯酸炔丙酯类化合物的Ireland-Claisen重排与Diels-Alder环加成的串联反应路线。