(1)Compared with the early phase cardioprotection induced by-opioid receptor agonist DADLE after CPB in swine, the late phase cardioprotection has more advantages.
2应用线粒体K_通道阻滞剂Glibenclamide能明显抑制δ阿片受体介导的猪CPBMI／R损伤早期时相的心肌保护作用。
The changes of TNF-α、IL-6、IL-8、SOD level in the NCG and CCG were observed from the blood samples of radius artery before operation, 1 hour after open chest and 1 hour after operation.
CPB手术对照组除与非CPB手术对照组同时点采血外，还分别与实验组同时点采集血标本，即在手术切皮前，主动脉阻断后15分钟，30分钟，术后1小时。
The vasomotion frequency and amplitude was positivelycorrelated with CPB flow rate.
血管运动频率和幅度与 CPB 流速呈正相关。
Hemodynamic data were assessedbefore, during, and after CPB.
血液动力学数据在 CPB 之前、CPB 时和 CPB 之后被收集。
Blood samples were obtained from right atrium, small pulmonary artry and venous line of CPB machine.
经Swanz-Ganz导管采右房、肺动脉血，转流中采机器静脉血。
Nine homogeneous polysaccharides were obtained for the first time from thewater and 5% NaOH extract of Salvia chinensis by using anion-exchange and gelfiltration chromatography repeatedly. Their structures were identified on the basis ofchemical methods (sugar component analysis, methylation analysis, partial acidhydrolysis, etc.) and spectral methods (〓 NMR, 〓NMR, 2D NMR, ESI-MS, IR, etc.) According to the pharmacological tests, the crude polysaccharide CPW and thehomogeneous polysaccharide SC1, SC2, SC3 and SC4 displayed remarkableimmunological activities.
石见穿全草分别用水和碱液提取，得到水提粗多糖CPW和碱提粗多糖CPB，经过DEAE-纤维素柱层析和凝胶渗透色谱反复分离纯化，首次从该植物中分得九个均一多糖组分，并通过各种化学方法(糖组分分析，甲基化分析以及部分酸水解等)和光谱方法(〓NMR，〓NMR，2D NMR，ESI-MS，IR等)研究了其结构特征。
Though the ways of cardiopulmonary bypass by three operative approaches with open beating heart surgery were different, the management of cardiopulmonary bypass was no significant difference.
不停跳下房间隔缺损修补术三种手术入径均是安全、可行的，微创小切口更优于胸骨正中切口，CPB建立方法虽有所不同，但其管理并无明显差异。
The change of temperature of ewes is active; the timing between ewe and fetus is excellent. Cooling of maternal bypass makes the decrease of fetal heart rate markedly, and fetal heart rate recovers to basal value following the rewarming phase. There were no marked effect of CPB on fetal mean BPs, however CPB impacted on blood flow of fetal brain and umbilical artery.
孕羊温度变化是主动的，两者同步性良好；母羊低温体外循环降温时引起胎羊心率明显下降，复温后胎心率能回复正常，体外循环对胎羊平均动脉压无明显影响，但低温降低胎羊脑部和脐动脉的血流。
METHODS Forty-five adult patients undergoing CABG open-heart procedure were randomized to three group. A: conventional CABG(on-pump, no ultrafiltration), B group:on-pump CABG with the zero-balance ultrafiltration and C group:OPCABG.
45例接受CABG的患者随机分为常规CPB组，常规CPB+零平衡超滤组和非体外循环组，每组各15例。
Management with prostacyclin during CPB might have the protective effect on the endothelial cells.
如果在CPB术中，采使用前列环素活性类药物治疗，可能对保护内皮细胞有积极意义。
Protamine the need to determine the dose. Anesthesia 1991, 46:925～928.7. Kuitunen AN, Salmenpera MT, Heinonen J. Heparin rebound: a comparative study of protamine chloride and protamine sulfate in patients undergoing coronary artery bypass surgery.
据上所述，CPB结束后应用鱼精蛋白中和肝素不能是一次性用药的行为，而应是一个边观察、边用药的递增过程，即首次剂量可按1：0.5给鱼精蛋白，然后每隔5～10 min补充10～20 mg，直至肝素血输完。
The blood-gas parameters were examined before and after CPB. Results The rabbit cardiopulmonary bypass model was established successfully.
但是由于兔的体重小，血容量少等特点，在有关兔CPB模型的文献中，都采用同种兔血预充才能顺利建立起兔CPB模型。
The primary cause of the acquired platelet defect is thought to be activation and release of alpha granules during extracorporeal circulation. Before CPB PRP was prepared by obtaining the required amount of patient`s whole blood by autologous plateletpheresis. PRP could be reinfused after operation in order to save the function and quantities of the platelets. On the other hand PRP could be made into autologous platelet gel. APG contains supraphysiologic amounts of growth factors and has adequate tensile strength and adhesive ability.
CPB前，利用自体血小板分离技术可将部分血小板从患者全血中分离出来制成富血小板血浆（Platelet-rich plasma PRP），PRP可在术后回输，以达到血小板数量和功能的双重保护，另一方面可将PRP制备成自体血小板胶，APG中含有丰富的生长因子，并且具有足够的抗张强度和粘性，因此可起到术中止血，封闭伤口，促进胸骨及伤口愈合的作用。
The primary cause of acquired platelet defect is thought to be activation and release of alpha granules during CPB. Before CPB, platelet-rich plasma was prepared by obtaining the required amount of patient`s whole blood by autologous plateletpheresis. PRP could be reinfused after operation in order to protect the function and quantities of the platelets. On the other hand, PRP could be made into autologous platelet gel. APG contains supraphysiologic amounts of growth factors, and has adequate tensile strength and adhesive ability. Therefore, it can be used for hemostasis in operation, sealing wound and enhancing incision or dehiscent sternal wounds healing.
CPB前，利用自体血小板分离技术可将部分血小板从患者全血中分离出来制成富血小板血浆(platelet-richplasma，PRP)，PRP可在术后回输，以达到血小板数量和功能的双重保护，另一方面可将PRP制备成自体血小板浆(autologousplateletgel，APG)，APG中含有丰富的生长因子，并且具有足够的抗张强度和粘性，因此可起到术中止血、封闭伤口、促进胸骨及伤口愈合的作用。
Specifically, five sections of work were carried out as follows:(1) Biocompatible polyvinyl alcohol and carboxyl-ended polybutadiene self-assembled into non-covalently connected micelles of-PVA with CPB core and PVA shell in water/THF (20/1, v/v).
具体开展了以下几方面的研究工作：（1）由生物相容的聚乙烯醇水溶液和端羧基聚丁二烯/四氢呋喃溶液，自组装形成了以CPB为核、PVA为壳的非共价键连接胶束－PVA，继而用戊二醛交联固定胶束的PVA壳，再用THF溶解空化胶束的CPB核，制得PVA纳米空心球。
After 10 min and 35 min of CPB, 400 L of air was injectedinto a bubble chamber in the CPB circuit.
结果提示给予 PFC 对减小 CPB 中出现的气泡体积可能是有用的。
RESULTS Accident was 0.33%(6/1800), including 1 case of insufficient capacity of oxygenation of bubble oxygenator, 1 case of blockage in hollow fiber membrance oxygenator, 1 case of aeroembolism in coronary artery, 2 cases of aeroembolism in artery tube and 1 case of venous cannalla slip out. There was no death.
结果 CPB期间发生意外事件6例(发生率为0.33%)：国产鼓泡肺氧合功能不良1例，进口膜肺中空纤维膜堵塞1例，冠状动脉内气栓1例、动脉管道气栓2例，静脉插管滑脱1例，经及时有效处理无致死病例。
RESULTS Accident was 0.33%(6/1800), including 1 case of insufficient capacity of oxygenation of bubble oxygenator, 1 case of blockage in hollow fiber membrance oxygenator, 1 case of aeroembolism in coronary artery, 2 cases of aeroembolism in artery tube and 1 case of venous cannalla slip out.
结果 CPB期间发生意外事件6例(发生率为0.33%)：国产鼓泡肺氧合功能不良1例，进口膜肺中空纤维膜堵塞1例，冠状动脉内气栓1例、动脉管道气栓2例，静脉插管滑脱1例，经及时有效处理无致死病例。
Methods: Ninety-seven cases of rheumatic heart disease were performed MVR by continuous suture with the heart beating under CPB with mild hypothermia.
对97例风湿性心脏病二尖瓣病变患者，在浅低温体外循环心脏不停跳的情况下，采用连续缝合方法进行人工机械二尖瓣置换术。
From Jan, 1984 to Dec, 1996, 78 cases died in 1709 patients and the mortality was 4.6%. From Jan, 1997 to Jan, 2004, 118 cases died in 5089 patients and the mortality was 2.3%. From March, 1997, to Dec, 2004, we performed 3748 patients undergoing CPB during open heart surgery with beating-heart surgery and there were no complications correlated with perfusion.
结果 全组死亡248例，占3.68%。1964年2月～1983年12月施行CPB手术464例，死亡52例，死亡率11.2%。1984年1月～1996年12月施行CPB手术1709例，死亡78例，死亡率4.6%。1997年1月～2004年12月施行CPB手术5089例，死亡118例，死亡率2.3%。1997年3月～2004年12月，对3748例患者采用心脏不停跳CPB，手术顺利，未发生与体外循环转流相关的并发症。