We hypothesized that such HIV suppression requires ACV phosphorylation by HHV kinases.
我们推测这种抑制作用依赖于人疱疹病毒酶导致的阿昔洛韦磷酸化。
If your going up against an allied player and you scout hes going to Cyro rush its only logical that you get some IFV's standing around in your base get at least 2 and some javalin soldiers to be complete sure your not going to lose any prospectors! Now if you think you got the micro you can use this against soviets. Just stack up 1 Riptide and 2 Guardian tanks one of them with the LAZOOR beam on. Now if he decides to spam Terror drones like a crazy person.
假设你认为你的操作足够好来对付苏联玩家，生产一个ACV跟两个坦克，其中一个坦克开瞄准激光，如果对方是一个海恐怖机器人的狂人，那么只要量产ACV并且堵在他的重工门口，任何刚刚生产出来的恐怖机器人都会被秒杀，之后就是你的守护者坦克开到他家并且结束对方。
RESULTS: The relative availability of multiple emulsion to tablet was 1498%. The t max and maitaining time for ACV concentration in plasma were both delayed.
结果：大鼠口服ACV 复乳对片剂的相对生物利用度为149－8％，达峰时间和血浓维持时间明显延迟。
WDT and ACV are ISO9000 international quality system certification.
WDT和ACV均获ISO9000国际质量体系认证。
WDT and ACV Security Industry will become a shining star.
WDT和ACV将成为安防行业一颗璀璨之星。
The morphology of tumor cells was observed and the change of quantity was assayed by trypan blue exclusion.
结果在 ACV作用下，GRC- 1细胞的形态及数量无明显改变；GRC- 1/ TK细胞被明显杀伤，数量明显减少，当含 2 5 。0 %GRC- 1/ TK细胞的混合培养细胞即可观察到明显杀伤作用。
After HSV-1 inoculating cornea 28 days different groups are divided. After taking oral traditional Chinese medicine 21 days, ultraviolet B is stimulated to activate latent HSV-1 in the treatment group to compare with ACV in the control group. HSV-1 positive rate was determined by virus titer of Cornea polish liquid technology to judge the recurrence rate of HSK. The control group is 72.72% and ACV group is 59.09%. Chinese medicine group is respectively 68.75%, 25.00% and 42.86%, Chinese medicine middle dose have significant difference with virus control groups (x〓=3.9923, p＜0.05). Although in other groups there is not significant difference with the contrast group of virus, little dose is too obvious to reduce recurrence rate of HSK.
在HSV-1接种鼠角膜后(Post inocuntion，p.i)的第28天开始分组治疗，于治疗后的第21天（p.i 49d），经紫外线B光照射，对潜伏的HSV-1进行激活后的第3天、第5天，采用角膜擦拭液病毒滴定法测定HSV-1阳性率（病毒致细胞病变，CPE）判断各组复发情况，计算复发率：病毒对照组为72.72%（16/22），无环鸟苷组为59.09%（13/22），角膜安高、中、低剂量组分别为68.75%（22/32）、25.0%（9/36）和42.86%（15/35），中剂量组与病毒对照组比较有显著性差异（x〓=3.9923，p＜0.05）。
Furthermore, phosphorylated ACV directly inhibits HIV-1 reverse transcriptase, terminating DNA chain elongation, and can trap RT at the termination site.
此外，磷酸化的阿昔洛韦能直接抑制HIV-1逆转录酶，将其阻止在终止位点，从而终止DNA链的延长。
For most viruses, there is aneed for antimicrobials that target unique viral molecular properties. Acycloviris one such drug. It is activated into ahuman herpesvirusDNA polymerase inhibitor exclusively by HHV kinases and, thus, does not suppress other viruses. Here, we show that ACV suppresses HIV-1in HHV-coinfected human tissues, but not in HHV-free tissue or cell cultures. However, addition of HHV-6-infected cells renders these cultures sensitive to anti-HIV ACV activity. We hypothesized that such HIV suppression requires ACV phosphorylation by HHV kinases. Indeed, an ACV monophosphorylated prodrug bypasses the HHV requirement for HIV suppression. Furthermore, phosphorylated ACV directly inhibits HIV-1reverse transcriptase, terminating DNA chain elongation, and can trap RT at the termination site. These data suggest that ACV anti-HIV-1activity may contribute to the response of HIV/HHV-coinfected patients to ACV treatment and could guide strategies for the development of new HIV-1RT inhibitors.
对大多数病毒而言，都需要有针对其分子特性的靶向杀毒剂阿昔洛韦就是这样一种靶向药物在人疱疹病毒酶的特定作用下，阿昔洛韦被激活成为人疱疹病毒DNA聚合酶抑制剂，因此不能再抑制其它的病毒我们的研究发现阿昔洛韦在共感染人疱疹病毒的组织中可以抑制HIV-1，但在无人疱疹病毒感染的组织或细胞中无此作用然而，加入人疱疹病毒-6感染的细胞却使得其对抗HIV的阿昔洛韦变得敏感我们推测这种抑制作用依赖于人疱疹病毒酶导致的阿昔洛韦磷酸化实际上，单磷酸化的阿昔洛韦前体药物无需人疱疹病毒的参与即可抑制HIV此外，磷酸化的阿昔洛韦能直接抑制HIV-1逆转录酶，将其阻止在终止位点，从而终止DNA链的延长这些结果提示阿昔洛韦的抗HIV-1活性决定了艾滋病病毒/人疱疹病毒共感染的患者对阿昔洛韦的治疗反应，也有助于开发新的HIV-1逆转录酶抑制剂
WDT Series Digital hard disk video recording system and embedded sub-PC has now become the industry's recording equipment to monitor the leader; ACV are well-known American brand, products include network video servers, network cameras, high-speed ball, speed ball, video cameras and so on.
WDT系列数字硬盘录像系统分PC式和嵌入式，现已成为行业内监控记录设备的领航者；ACV是美国知名品牌，产品包括网络视频服务器、网络摄像机、高速球、恒速球、摄像机等。
The Watts ACV 100D-B deluge valve meets all requirements for UL Listed, fire protection service.
美国瓦茨ACV 110D-B喷淋控制阀满足所有消防应用的美国UL认证的要求。
The Watts ACV 100D-A deluge valve meets all requirements for UL Listed, fire protection service.
美国瓦茨ACV 110D-A喷淋控制阀满足所有消防应用的美国UL认证的要求。
Now if you think you got the micro you can use this against soviets. Just stack up 1 Riptide and 2 Guardian tanks one of them with the LAZOOR beam on. Now if he decides to spam Terror drones like a crazy person. Mass riptides till you get to camp hes War Factory and can kill any Terror drone that gets out. Then just simply roll Guardian tanks into hes base to finish up the job!.
假设你认为你的操作足够好来对付苏联玩家，生产一个ACV跟两个坦克，其中一个坦克开瞄准激光，如果对方是一个海恐怖机器人的狂人，那么只要量产ACV并且堵在他的重工门口，任何刚刚生产出来的恐怖机器人都会被秒杀，之后就是你的守护者坦克开到他家并且结束对方。
The experimental data shows that ACV has no regulating immune action, though ACV group can reduce certain recurring rate.
目前研究认为CD8〓T细胞对维持病毒在TG内潜伏防止病毒活化起着重要的作用。
Objective: To observe the clinical effect of modified Yinqiao powder combining acyclovir (ACV) in the treatment of herpes simplex virus keratitis (epithelial).
目的观察增损银翘散联合无环鸟苷治疗单纯疱疹病毒性角膜炎（上皮型）的临床疗效。
Objective To set up a method to determine the concentration of Acyclovir (ACV) in Muan eye ointment with HPLC for the study of the ointment pharmacokinetics in rabbit aqueous humor.
目的建立HPLC法测定目安眼膏在家兔房水内阿昔洛韦（ACV）含量的方法，为目安眼膏在兔眼内转运动力学研究提供定量方法。
Acyclovir palmitate (ACVP) was synthesized from acyclovir (ACV) and palmitoyl chloride.
本论文以阿昔洛韦（Acyclovir，ACV）为原料与棕榈酰氯反应合成了阿昔洛韦棕榈酸酯（AcyclovirPalmitate，ACVP）。
Aciclovir (ACV), thymic peptide and interferon (IFN) showed significant effects of anti virus and immunoregulation.
阿昔洛韦、胸腺肽及干扰素抗病毒和调节免疫疗效显著。
METHODS Rabbit keratitis models were established by intrastroma injection of culture medium containing either bacillus pyocyaneus or staphylococcus aureus.
阳性对照药ACV无任何疗效。方法：于家兔角膜实质层分别注射接种金黄色葡萄球菌和绿脓杆菌制成两种角膜炎模型。
Because of the structural specificity, as for maneuver ACV is very different from a general ship.
由于结构的特殊性，全垫升气垫船在操纵方面与常规船舶有很大差别。